T-Box 1 抗体 (AA 200-410)
Our Local Distributor
北京 101111
Quick Overview for T-Box 1 抗体 (AA 200-410) (ABIN5027059)
抗原
See all T-Box 1 (TBX1) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 200-410
-
纯化方法
- Protein A Chromatography
-
免疫原
- A partial length recombinant Brachyury protein (amino acids 200-410) was used as the immunogen for this antibody.
-
亚型
- IgG
-
-
-
-
应用备注
- WB: 2-4 μg/mL
-
限制
- 仅限研究用
-
-
-
浓度
- 0.5 mg/mL
-
缓冲液
- PBS containing 0.05 % BSA, PH 7.4
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
-
-
- T-Box 1 (TBX1)
-
别名
- Brachyury
-
背景
- Brachyury is a transcription factor encoded by T, a member of the T-box gene family, and required for posterior mesoderm formation and differentiation as well as for notochord development. It is expressed in all nascent mesoderm, in the embryo. Along with embryonic differentiation, it is downregulated, restricted into the notochord and the tail bud, and then lost, when notochordal cells are replaced by bone in the vertebral bodies and by the nucleus pulposus in the intervertebral discs. In the adult, brachyury expression has been found in chordoma, a malignant tumor which recapitulates notochord and derives from small collections of notochordal cells which may persist into the adult life.
-
分子量
- 55 kDa
-
基因ID
- 6862
-
UniProt
- O15178
-
途径
- Retinoic Acid Receptor Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation
抗原
-