BCL6 抗体 (AA 200-401)
Quick Overview for BCL6 抗体 (AA 200-401) (ABIN5027051)
抗原
See all BCL6 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
抗原表位
- AA 200-401
-
纯化方法
- Protein G Chromatography
-
免疫原
- A partial length recombinant BCL-6 protein (amino acids 200-401) was used as the immunogen for this antibody.
-
亚型
- IgG2b kappa
-
-
anti-B-Cell CLL/lymphoma 6 (BCL6) (AA 501-600) antibody
BCL6 适用: 人, 小鼠 WB, ELISA, IHC (p), IF (cc), IHC (fro), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 6 (BCL6) (Internal Region) antibodyBCL6 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 6 (BCL6) (AA 256-389) antibodyBCL6 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal BCL6-1527 unconjugated
anti-B-Cell CLL/lymphoma 6 (BCL6) (Internal Region) antibodyBCL6 适用: 人, 小鼠 WB, IHC (p), IP, ChIP 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 6 (BCL6) (AA 147-276) antibodyBCL6 适用: 人 FACS, ELISA, ICC 宿主: 小鼠 Monoclonal 2G1B6 unconjugated
anti-B-Cell CLL/lymphoma 6 (BCL6) (Internal Region) antibodyBCL6 适用: 人, 大鼠 WB, IHC, IF, ELISA, ICC 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 6 (BCL6) (AA 519-547) antibodyBCL6 适用: 人, 小鼠 WB, IHC, FACS, ELISA 宿主: 兔 Polyclonal unconjugated
anti-B-Cell CLL/lymphoma 6 (BCL6) (AA 256-389) antibodyBCL6 适用: 人 WB 宿主: 小鼠 Monoclonal BCL6-1475 unconjugated
anti-B-Cell CLL/lymphoma 6 (BCL6) (AA 256-389) antibodyBCL6 适用: 人 IHC, ELISA, StM, Coat 宿主: 小鼠 Monoclonal BCL6-1982 unconjugated
anti-B-Cell CLL/lymphoma 6 (BCL6) (pSer333) antibodyBCL6 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- WB: 2-4 μg/mL
-
限制
- 仅限研究用
-
-
-
浓度
- 0.5 mg/mL
-
缓冲液
- PBS containing 0.05 % BSA, PH 7.4
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
-
-
- BCL6 (B-Cell CLL/lymphoma 6 (BCL6))
-
别名
- BCL-6
-
背景
- BCL6 (B-cell lymphoma 6) is a 95 kDa zinc finger transcription factor and contains an N-terminal POZ domain. BCL6 is a transcriptional repressor and a master regulator of the germinal center (GC) B cell phenotype controlling its development and growth. BCL-6 modulates IL-4, BCR, and CD40L signals for normal B cell development. Altered BCL6 protein expression is implicated in pathogenesis of diverse human hematologic malignancies, especially in the diffuse large B cell lymphoma (DLBCL), the most common lymphoma in adults. BCL6 suppresses the expression of p53 (also known as tp53) tumor suppressor gene and modulates DNA damage-induced apoptotic responses in GC B cells.
-
分子量
- 72 kDa
-
基因ID
- 604
-
UniProt
- P41182
-
途径
- Chromatin Binding, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus
抗原
-
