ALDH1A1 抗体 (AA 284-492)
Quick Overview for ALDH1A1 抗体 (AA 284-492) (ABIN5027017)
抗原
See all ALDH1A1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 284-492
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纯化方法
- Protein A Chromatography
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免疫原
- A partial length recombinant ALDH1A1 protein (amino acids 284-492) was used as the immunogen for this antibody.
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亚型
- IgG
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anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 48-147) antibody
ALDH1A1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 2-501) antibodyALDH1A1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (C-Term) antibodyVerified ALDH1A1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 1-501) antibodyALDH1A1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) antibodyALDH1A1 适用: 人 WB, IF, IP 宿主: 兔 Monoclonal unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (C-Term) antibodyALDH1A1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 1-110) antibodyALDH1A1 适用: 人 WB, IHC, ELISA, FACS 宿主: 小鼠 Monoclonal 2B2G1 unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 1-326) antibodyALDH1A1 适用: 小鼠 WB, IHC, FACS, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 315-434) antibodyALDH1A1 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal ALDH1A1-1381 unconjugated
anti-Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1) (AA 1-501) antibodyALDH1A1 适用: 人 WB, ELISA, IHC (p), IP 宿主: 小鼠 Monoclonal 1G6 unconjugated
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应用备注
- WB: 1-2 μg/mL
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- PBS containing 0.05 % BSA, PH 7.4
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
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- ALDH1A1 (Aldehyde Dehydrogenase 1 Family, Member A1 (ALDH1A1))
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别名
- ALDH1A1
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背景
- Aldehyde dehydrogenase 1A1 (ALDH1A1) is a member of a superfamily of detoxification enzymes found in various tissues that participate in the oxidation of both aliphatic and aromatic aldehydes. The human ALDH1A1, which is tetrameric and predominantly of cytosolic origin, functions mainly in acetaldehyde and neurotransmitter metabolism. It is also reported to play a major role in the production of retinoic acid, which is important for gene expression and tissue differentiation, and also in cyclophosphamide detoxification. ALDH1A1 is found in various tissues, including the central nervous system (CNS), with highest levels in the liver. In the brain, ALDH1A1 participates in the metabolism of catecholamines including dopamine (DA) and norepinephrine, and is uniquely expressed in a subset of dopaminergic (DAergic) neurons in the ventral mesencephalon where it converts 3,4-dihydroxyphenylacetaldehyde, a potentially toxic aldehyde, to 3,4-dihydroxyphenylacetic acid, a non toxic metabolite. ALDHA1 has been implicated in the development of alcohol dependence and other alcohol-use disorders, alcohol-induced flushing and sensitivity to alcohol.
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分子量
- 55 kDa
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基因ID
- 216
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UniProt
- P00352
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途径
- Dopaminergic Neurogenesis
抗原
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