Elastase 抗体
This anti-Elastase antibody is a 小鸡 多克隆 antibody detecting Elastase in ELISA, WB, IHC 和 AGG. Suitable for 哺乳动物.
Quick Overview for Elastase 抗体 (ABIN5026899)
抗原
See all Elastase 抗体
Elastase
适用
哺乳动物
宿主
小鸡
克隆类型
多克隆
标记
This Elastase antibody is un-conjugated
应用范围
ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Agglutination (AGG)
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产品特性
- IgY-antibody
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纯化方法
- Precipitation with ammoniumsulfate , dialyse and fitration
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免疫原
- raw, native protein
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亚型
- IgY
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应用备注
- Perform a chessboard titation before the first application
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- PBS, pH 7.4, 0.1 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C/-20 °C
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- Elastase
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背景
- Secreted by neutrophils and macrophages during inflammation, elastase is a serine proteinase in the same family as chymotrypsin and has broad substrate specificity, destroys bacteria and host tissue. This protein degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. The enzyme may play a role in degenerative and inflammatory diseases by its proteolysis of collagen-IV and elastin of the extracellular matrix. It is also an important protease enzyme that when expressed aberrantly can cause emphysema or emphysematous changes. This involves breakdown of the lung structure and increased airspaces.
抗原
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