Elastase 抗体
Our Local Distributor
北京 101111
Quick Overview for Elastase 抗体 (ABIN5026899)
抗原
See all Elastase 抗体适用
宿主
克隆类型
标记
应用范围
-
-
产品特性
- IgY-antibody
-
纯化方法
- Precipitation with ammoniumsulfate , dialyse and fitration
-
免疫原
- raw, native protein
-
亚型
- IgY
-
-
-
-
应用备注
- Perform a chessboard titation before the first application
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 mg/mL
-
缓冲液
- PBS, pH 7.4, 0.1 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C/-20 °C
-
-
- Elastase
-
背景
- Secreted by neutrophils and macrophages during inflammation, elastase is a serine proteinase in the same family as chymotrypsin and has broad substrate specificity, destroys bacteria and host tissue. This protein degrades the outer membrane protein A (OmpA) of E. coli as well as the virulence factors of such bacteria as Shigella, Salmonella and Yersinia. The enzyme may play a role in degenerative and inflammatory diseases by its proteolysis of collagen-IV and elastin of the extracellular matrix. It is also an important protease enzyme that when expressed aberrantly can cause emphysema or emphysematous changes. This involves breakdown of the lung structure and increased airspaces.
抗原
-