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PF4 抗体

This anti-PF4 antibody is a 小鸡 多克隆 antibody detecting PF4 in WB, IHC, ELISA 和 AGG. Suitable for 哺乳动物.
产品编号 ABIN5026898
发货至: 中国

Quick Overview for PF4 抗体 (ABIN5026898)

抗原

See all PF4 抗体
PF4 (Platelet Factor 4 (PF4))

适用

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  • 1
哺乳动物

宿主

  • 88
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  • 5
  • 1
  • 1
小鸡

克隆类型

  • 92
  • 34
多克隆

标记

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  • 1
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This PF4 antibody is un-conjugated

应用范围

  • 101
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Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Agglutination (AGG)
  • 产品特性

    IgY-antibody

    纯化方法

    Precipitation with ammoniumsulfate , dialyse and fitration

    免疫原

    raw, native protein

    亚型

    IgY
  • 应用备注

    Perform a chessboard titation before the first application

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    PBS, pH 7.4, 0.1 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C
  • 抗原

    PF4 (Platelet Factor 4 (PF4))

    别名

    Platelet-factor 4

    背景

    Platelet-Factor 4 (PF4) complex is the antigen in heparin-induced thrombocytopenia (HIT), an idiosyncratic autoimmune reaction to the administration of the anticoagulant heparin. Its autoantibodies have also been found in patients with thrombosis with similar HIT although they have received no prior administration of heparin. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair. It is usually found in a complex with proteoglycan.
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