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MLXIPL 抗体 (AA 81-180) (AbBy Fluor® 750)

This anti-MLXIPL antibody (ABIN5012474) is a Rabbit Polyclonal antibody detecting MLXIPL in IF (cc), IF (p). Suitable for Rat.
产品编号 ABIN5012474
发货至: 中国

Quick Overview for MLXIPL 抗体 (AA 81-180) (AbBy Fluor® 750) (ABIN5012474)

抗原

See all MLXIPL 抗体
MLXIPL (MLX Interacting Protein-Like (MLXIPL))

适用

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大鼠

宿主

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克隆类型

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多克隆

标记

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This MLXIPL antibody is conjugated to AbBy Fluor® 750

应用范围

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Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    AA 81-180

    交叉反应

    大鼠

    预测反应

    Human,Mouse,Dog,Cow,Pig,Horse,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human WBSCR14/ChREBP

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    MLXIPL (MLX Interacting Protein-Like (MLXIPL))

    别名

    WBSCR14

    背景

    Synonyms: ChREBP, bHLHd14, Carbohydrate responsive element binding protein, MIO, MLX interacting protein like, Mlx interactor, MLXIPL, MONDOB, WBSCR 14, WBSCR14, Williams Beuren syndrome chromosome region 14, Williams Beuren syndrome chromosome region 14 protein, WS basic helix loop helix leucine zipper protein, WS bHLH, MLXPL_HUMAN.

    Background: ChREBP (Carbohydrate responsive element binding protein) is a transcription factor playing a critical role in the nutrient and hormonal regulation of genes encoding enzymes of glucose metabolism and lipogenesis pathways. It contains several domains including a nuclear localization signal (NLS) near the N-terminus, polyproline domains, a basic helix-loop-helix leucine zipper (b/HLH/Zip) and a leucine zipper like (zip-like) domain.ChREBP is ubiquitously detected in various tissues, with highest expression in liver, kidney and white and brown adipose tissue. Under basal conditions ChREBP is localized in the cytosol, translocating into the nucleus upon high glucose stimulation following its dephosphorylation of serine 196.

    基因ID

    51085

    途径

    Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process
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