Thymidine Phosphorylase 抗体 (AA 121-220) (AbBy Fluor® 750)
Quick Overview for Thymidine Phosphorylase 抗体 (AA 121-220) (AbBy Fluor® 750) (ABIN5011816)
抗原
See all Thymidine Phosphorylase (TYMP) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - AA 121-220
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交叉反应
 - 人
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纯化方法
 - Purified by Protein A.
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免疫原
 - KLH conjugated synthetic peptide derived from human Thymidine Phosphorylase
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亚型
 - IgG
 
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应用备注
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                        IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 
                                            
限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - 1 μg/μL
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缓冲液
 - Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
 - ProClin
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注意事项
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
 - -20 °C
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储存方法
 - Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
 - 12 months
 
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- Thymidine Phosphorylase (TYMP)
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别名
 - TP/thymidine phosphorylase
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背景
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Synonyms: ECGF 1, PDEGF, ECGF1, Endothelial cell growth factor 1, Endothelial cell growth factor 1 platelet derived, Gliostatin, hPD ECGF, MNGIE, PD ECGF, PDECGF, PDEGF, Platelet derived endothelial growth factor, TdRPase, TP, TYMP, Thymidine Phosphorylase, TYPH_HUMAN, TdRPase.
Background: In the presence of inorganic orthophosphate, the platelet-derived endothelial growth factor (PD-ECGF) thymidine phosphorylase (TP) (gliostatin) catalyses the reversible phospholytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It is both chemotactic and mitogenic for endothelial cells and a non-heparin binding angiogenic factor present in platelets. It is also involved in transformation of fluoropyrimidines, cytotoxic agents used in the treatment of a variety of malignancies, into active cytotoxic metabolites.
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基因ID
 - 1890
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途径
 - Signaling Events mediated by VEGFR1 and VEGFR2
 
抗原
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