ZSCAN4 抗体 (C-Term)
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Quick Overview for ZSCAN4 抗体 (C-Term) (ABIN501165)
抗原
See all ZSCAN4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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交叉反应 (详细)
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Affinity chromatography
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免疫原
- 18 amino acid peptide near the carboxy terminus of human ZSCAN4
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亚型
- IgG
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应用备注
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ELISA. Immunohistochemistry on paraffin sections. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- ZSCAN4 (Zinc Finger and SCAN Domain Containing 4 (ZSCAN4))
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别名
- ZSCAN4
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背景
- Zytotic genome activation (ZGA) is the first and most critical transition event from the maternal genetic to the embryonic genetic program and the major burst of ZGA occurs only in the late 2-cell stage. ZSCAN4 encodes a SCAN domain and four zinc finger domains and is expressed in late 2-cell embryos and embryonic stem cells. Loss-of-function studies using siRNA shows delays in the progression from the 2-cell to the 4-cell stage and subsequent embryo development. ZSCAN4 plays an important role in the preimplantation development. Also, ZSCAN4 is involved in telomere maintenance and long term genomic stability in ES cells, suggesting that ZSCAN4 may be of critical importance in maintaining pluripotency in replicating stem cells.Synonyms: ZNF494, Zinc finger and SCAN domain-containing protein 4, Zinc finger protein 494
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基因ID
- 201516
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NCBI登录号
- NP_689890
抗原
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