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TXN2 抗体 (AA 101-166) (AbBy Fluor® 750)

This anti-TXN2 antibody is a 兔 多克隆 antibody detecting TXN2 in WB, IF (cc) 和 IF (p). Suitable for 大鼠.
产品编号 ABIN5011557
发货至: 中国

Quick Overview for TXN2 抗体 (AA 101-166) (AbBy Fluor® 750) (ABIN5011557)

抗原

See all TXN2 抗体
TXN2 (Thioredoxin 2 (TXN2))

适用

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  • 2
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  • 2
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  • 2
  • 1
  • 1
大鼠

宿主

  • 51
  • 3

克隆类型

  • 48
  • 6
多克隆

标记

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  • 1
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  • 1
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  • 1
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  • 1
This TXN2 antibody is conjugated to AbBy Fluor® 750

应用范围

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 15
    • 14
    • 8
    • 6
    • 3
    • 1
    AA 101-166

    交叉反应

    大鼠

    预测反应

    Human,Mouse,Dog,Cow,Pig,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Thioredoxin 2

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    TXN2 (Thioredoxin 2 (TXN2))

    别名

    Thioredoxin 2

    背景

    Synonyms: mitochondrial thioredoxin, MT-TRX, MTRX, thioredoxin 2 precursor, Thioredoxin mitochondrial, Thioredoxin2, TRX 2, TRX2, TXN 2, TXN2.

    Background: Thioredoxins (Trx) are small, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells. Trx contains a redox-active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. The two cysteine residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds. Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor. The reduced Trx is a hydrogen donor for ribonucleotide reductase, the essential enzyme for DNA synthesis, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations. Specific protein disulfide targets for reduction by Trx include protein disulfide isomerase(PDI) and a number of transcription factors such as p53, NF-kB and AP-1. Trx is also capable of removing H2O2, particularly when it is coupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins.

    基因ID

    25828

    途径

    Cell RedoxHomeostasis
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