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ZNF350 抗体 (C-Term)

ZNF350 适用: 人, 小鼠, 大鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN501145
发货至: 中国
  • 抗原 See all ZNF350 抗体
    ZNF350 (Zinc Finger Protein 350 (ZNF350))
    抗原表位
    • 15
    • 7
    • 7
    • 6
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 43
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 39
    • 4
    克隆类型
    • 41
    • 2
    多克隆
    标记
    • 19
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ZNF350 antibody is un-conjugated
    应用范围
    • 27
    • 19
    • 13
    • 13
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects ZNF350.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Affinity chromatography
    免疫原
    ZBRK1 antibody was raised against a 20 amino acid peptide near the carboxy terminus of the human ZBRK1.
    亚型
    IgG
    Top Product
    Discover our top product ZNF350 Primary Antibody
  • 应用备注
    ELISA. Western blot: 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    ZNF350 (Zinc Finger Protein 350 (ZNF350))
    别名
    ZNF350 (ZNF350 产品)
    别名
    ZFQR antibody, ZBRK1 antibody, zinc finger protein 350 antibody, ZNF350 antibody, znf350 antibody
    背景
    ZBRK1 is a member of the Kruppel-associated box-zinc finger protein (KRAB-ZFP) protein family of transcriptional repressors. ZBRK1 has been shown to not only be up-regulated in senescent fibroblasts but also interacts with BRCA1, a transcriptional regulator with tumor suppressor activity. ZBRK1 binds to a specific sequence within the GADD45 gene, supporting the assembly of a nuclear complex containing BRCA1 and repressing its transcription. Recent experiments demonstrate that ZBRK1 can homo-oligomerize in vitro and in vivo through a C-terminal transcriptional repression domain (CTRD), and this oligomerization facilitates the ZBRK1-directed transcriptional repression through ZBRK1 response elements. These results suggest that higher order ZBRK1 oligomers may assemble through both protein-DNA and CTRD-dependent protein-protein interactions.Synonyms: KRAB zinc finger protein ZFQR, ZBRK1, ZFQR, Zinc finger and BRCA1-interacting protein with a KRAB domain 1, Zinc finger protein 350, Zinc finger protein ZBRK1
    基因ID
    59348
    NCBI登录号
    NP_067645
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