ZNF350 抗体 (C-Term)
Quick Overview for ZNF350 抗体 (C-Term) (ABIN501145)
抗原
See all ZNF350 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects ZNF350.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Affinity chromatography
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免疫原
- ZBRK1 antibody was raised against a 20 amino acid peptide near the carboxy terminus of the human ZBRK1.
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亚型
- IgG
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anti-Zinc Finger Protein 350 (ZNF350) (AA 1-532) antibody
ZNF350 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1A9 unconjugated
anti-Zinc Finger Protein 350 (ZNF350) (AA 1-532) antibodyZNF350 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Zinc Finger Protein 350 (ZNF350) (AA 1-532) antibodyZNF350 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 350 (ZNF350) (AA 108-157) antibodyZNF350 适用: 人, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 350 (ZNF350) (AA 119-168) antibodyZNF350 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 350 (ZNF350) (AA 233-532) antibodyZNF350 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- ZNF350 (Zinc Finger Protein 350 (ZNF350))
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别名
- ZNF350
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背景
- ZBRK1 is a member of the Kruppel-associated box-zinc finger protein (KRAB-ZFP) protein family of transcriptional repressors. ZBRK1 has been shown to not only be up-regulated in senescent fibroblasts but also interacts with BRCA1, a transcriptional regulator with tumor suppressor activity. ZBRK1 binds to a specific sequence within the GADD45 gene, supporting the assembly of a nuclear complex containing BRCA1 and repressing its transcription. Recent experiments demonstrate that ZBRK1 can homo-oligomerize in vitro and in vivo through a C-terminal transcriptional repression domain (CTRD), and this oligomerization facilitates the ZBRK1-directed transcriptional repression through ZBRK1 response elements. These results suggest that higher order ZBRK1 oligomers may assemble through both protein-DNA and CTRD-dependent protein-protein interactions.Synonyms: KRAB zinc finger protein ZFQR, ZBRK1, ZFQR, Zinc finger and BRCA1-interacting protein with a KRAB domain 1, Zinc finger protein 350, Zinc finger protein ZBRK1
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基因ID
- 59348
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NCBI登录号
- NP_067645
抗原
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