ZNF350 抗体 (C-Term)
Our Local Distributor
北京 101111
Quick Overview for ZNF350 抗体 (C-Term) (ABIN501145)
抗原
See all ZNF350 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
特异性
- This antibody detects ZNF350.
-
交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
-
纯化方法
- Affinity chromatography
-
免疫原
- ZBRK1 antibody was raised against a 20 amino acid peptide near the carboxy terminus of the human ZBRK1.
-
亚型
- IgG
-
-
anti-Zinc Finger Protein 350 (ZNF350) (AA 1-532) antibody
ZNF350 适用: 人 WB, ELISA, IP 宿主: 小鼠 Monoclonal 1A9 unconjugated
anti-Zinc Finger Protein 350 (ZNF350) (AA 233-532) antibodyZNF350 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 350 (ZNF350) (AA 1-532) antibodyZNF350 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-Zinc Finger Protein 350 (ZNF350) (AA 233-532) antibodyZNF350 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 350 (ZNF350) (AA 1-532) antibodyZNF350 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 350 (ZNF350) (AA 108-157) antibodyZNF350 适用: 人, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger Protein 350 (ZNF350) (AA 119-168) antibodyZNF350 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
-
ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
缓冲液
- PBS containing 0.02 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
-
-
- ZNF350 (Zinc Finger Protein 350 (ZNF350))
-
别名
- ZNF350
-
背景
- ZBRK1 is a member of the Kruppel-associated box-zinc finger protein (KRAB-ZFP) protein family of transcriptional repressors. ZBRK1 has been shown to not only be up-regulated in senescent fibroblasts but also interacts with BRCA1, a transcriptional regulator with tumor suppressor activity. ZBRK1 binds to a specific sequence within the GADD45 gene, supporting the assembly of a nuclear complex containing BRCA1 and repressing its transcription. Recent experiments demonstrate that ZBRK1 can homo-oligomerize in vitro and in vivo through a C-terminal transcriptional repression domain (CTRD), and this oligomerization facilitates the ZBRK1-directed transcriptional repression through ZBRK1 response elements. These results suggest that higher order ZBRK1 oligomers may assemble through both protein-DNA and CTRD-dependent protein-protein interactions.Synonyms: KRAB zinc finger protein ZFQR, ZBRK1, ZFQR, Zinc finger and BRCA1-interacting protein with a KRAB domain 1, Zinc finger protein 350, Zinc finger protein ZBRK1
-
基因ID
- 59348
-
NCBI登录号
- NP_067645
抗原
-
