Ectodysplasin A2 Receptor 抗体
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Quick Overview for Ectodysplasin A2 Receptor 抗体 (ABIN501133)
抗原
See all Ectodysplasin A2 Receptor (EDA2R) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects EDA2R / TNFRSF27.
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交叉反应 （详细）
- Species reactivity (tested):Human
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纯化方法
- Affiinity chromatography
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免疫原
- XEDAR antibody was raised against recombinant human XEDAR.
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亚型
- IgG
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anti-Ectodysplasin A2 Receptor (EDA2R) (AA 1-138) antibody
EDA2R 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 4A6B4 unconjugated
anti-Ectodysplasin A2 Receptor (EDA2R) (AA 1-138) antibodyEDA2R 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ectodysplasin A2 Receptor (EDA2R) (AA 1-297) antibodyEDA2R 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Ectodysplasin A2 Receptor (EDA2R) (AA 1-297) antibodyEDA2R 适用: 人 WB, FACS 宿主: 小鼠 Polyclonal unconjugated
anti-Ectodysplasin A2 Receptor (EDA2R) (AA 1-110) antibodyEDA2R 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C1 unconjugated
anti-Ectodysplasin A2 Receptor (EDA2R) (AA 51-150) antibodyEDA2R 适用: 人, 小鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Ectodysplasin A2 Receptor (EDA2R) (AA 2-135) antibodyEDA2R 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A10 unconjugated
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应用备注
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ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistrry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- Ectodysplasin A2 Receptor (EDA2R)
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别名
- EDA2R / TNFRSF27
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背景
- X-linked ectodysplasin-A2 receptor (XEDAR) is a recently isolated member of the tumor necrosis factor receptor family that is highly expressed during embryonic development and binds to ectodysplatin-A2 (EDA-A2) (1). Two predominantly expressed isoforms, XEDAR-s and XEDAR-L, differ by only a 21-amino region at the juxtamembrane region of the cytoplasmic domain. Neither isoform possesses a death domain and both have been shown to act mainly through TRAF3 and TRAF6 to activate the NF-kappaB and JNK pathways (2). Cells transfected with XEDAR and treated with EDA-A2 cause the assembly of a secondary complex containing FADD, caspase-8 and caspase-10, leading to the activation caspase-8 and caspase-3, and finally apoptosis (3). The EDA-A2-induced apoptosis is dependent on caspase-9 activation, as various pharmacological and genetic inhibitors of caspase-8 blocked apoptosis following EDA-A2 treatment (3).Synonyms: EDA-A2 receptor, Tumor necrosis factor receptor superfamily member 27, UNQ2448/PRO5727/PRO34080, X-linked ectodysplasin-A2 receptor, XEDAR
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基因ID
- 60401
抗原
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