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Supervillin 抗体 (AA 51-150) (AbBy Fluor® 750)

This anti-Supervillin antibody is a 兔 多克隆 antibody detecting Supervillin in WB, IF (cc) 和 IF (p). Suitable for 小鼠.
产品编号 ABIN5011184
发货至: 中国

Quick Overview for Supervillin 抗体 (AA 51-150) (AbBy Fluor® 750) (ABIN5011184)

抗原

See all Supervillin (SVIL) 抗体
Supervillin (SVIL)

适用

  • 22
  • 15
小鼠

宿主

  • 29
  • 6
  • 1

克隆类型

  • 31
  • 5
多克隆

标记

  • 14
  • 6
  • 5
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Supervillin antibody is conjugated to AbBy Fluor® 750

应用范围

  • 36
  • 12
  • 12
  • 12
  • 12
  • 7
  • 7
  • 4
  • 3
  • 3
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 6
    • 5
    • 2
    • 1
    • 1
    AA 51-150

    交叉反应

    小鼠

    预测反应

    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Supervillin

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Supervillin (SVIL)

    别名

    Supervillin

    背景

    Synonyms: Supervillin, Archvillin, p205/p250, SVIL

    Background: Forms a high-affinity link between the actin cytoskeleton and the membrane. Isoform 1 (archvillin) is among the first costameric proteins to assemble during myogenesis and it contributes to myogenic membrane structure and differentiation. Appears to be involved in myosin II assembly. May modulate myosin II regulation through MLCK during cell spreading, an initial step in cell migration. May play a role in invadopodial function. Isoform 2 may be involved in modulation of focal adhesions. Supervillin-mediated down-regulation of focal adhesions involves binding to TRIP6. Plays a role in cytokinesis through KIF14 interaction (By similarity).

    基因ID

    6840

    UniProt

    O95425
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