VGF 抗体 (C-Term)
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Quick Overview for VGF 抗体 (C-Term) (ABIN501116)
抗原
See all VGF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects VGF.
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交叉反应 (详细)
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Affinity chromatography
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免疫原
- VGF antibody was raised against a 17 amino acid peptide near the carboxy terminus of the human VGF.
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亚型
- IgG
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应用备注
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ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- VGF (VGF Nerve Growth Factor Inducible (VGF))
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别名
- VGF
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背景
- VGF was initially identified as a rapidly regulated gene product in nerve growth factor-treated PC12 cells. This protein is synthesized in neurons in the central and peripheral nervous system as well as in the pituitary, adrenal medulla, endocrine cells of the stomach, and pancreatic beta cells. VGF is thought to be involved in organism energy balance and regulation of homeostasis as mice lacking this gene show deficits in these areas. More recent results suggest that VGF is upregulated by brain-derived neurotrophic factor (BDNF) and can stimulate the proliferation of hippocampal progenitor cells and produce antidepressant-like behavioral effects, suggesting that this pathway may be a suitable target for therapeutic treatments.Synonyms: Neurosecretory protein VGF
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基因ID
- 7425
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NCBI登录号
- NP_003369
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途径
- Hormone Transport, Carbohydrate Homeostasis
抗原
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