TTC5 抗体 (C-Term)
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Quick Overview for TTC5 抗体 (C-Term) (ABIN501091)
抗原
See all TTC5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects TTC5
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交叉反应 (详细)
- Species reactivity (tested):Human, mouse
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纯化方法
- Affinity chromatography
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免疫原
- TTC5 antibody was raised against a 14 amino acid peptide from near the carboxy terminus of human TTC5.
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亚型
- IgG
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应用备注
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ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- TTC5 (Tetratricopeptide Repeat Domain 5 (TTC5))
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别名
- TTC5
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背景
- Tetratricopeptide repeat protein 5 (TTC5) is a member of a diverse group of functionally distinct proteins that are characterized by containing one or more tetratricopeptide repeats (1). Each motif consists of two anti-parallel a-helices such that tandem arrays of TPR motifs generate a right-handed helical structure with an amphipathic channel that may serve to accommodate the complementary region of a target protein. While the exact function of TTC5 remains unclear, it is thought that the TPR motifs serve to mediate protein-protein interactions such as those seen with protein chaperones HSP70 and HSP90 (2) and some proteins involved in cell stress response signaling pathways such as protein phosphatase 5 (3), suggesting that TTC5 may also function via protein-protein interactions mediated by its TPR motifs.Synonyms: TPR repeat protein 5, Tetratricopeptide repeat protein 5
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基因ID
- 91875
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UniProt
- Q8N0Z6
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途径
- Chromatin Binding
抗原
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