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CRLF2 抗体 (Center)

This anti-CRLF2 antibody is a 兔 多克隆 antibody detecting CRLF2 in WB, IHC (p) 和 EIA. Suitable for 人.
产品编号 ABIN501083
发货至: 中国

Quick Overview for CRLF2 抗体 (Center) (ABIN501083)

抗原

See all CRLF2 抗体
CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))

适用

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宿主

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克隆类型

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多克隆

标记

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This CRLF2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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    Center

    特异性

    This antibody detects CRLF2.

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Peptide affinity chromatography

    免疫原

    TSLP Receptor antibody was raised against a 19 amino acid peptide from near the center of human TSLP receptor.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    CRLF2 (Cytokine Receptor-Like Factor 2 (CRLF2))

    别名

    CRLF2

    背景

    Thymic stromal lymphopoietin (TSLP) has recently been identified as an important factor capable of driving dendritic cell maturation and activation. It is involved in the positive selection of regulatory T cells, maintenance of peripheral CD4+ T cell homeostasis and the induction of CD4+ T cell-mediated allergic reaction. TSLP is also capable of supporting the growth of fetal liver and adult B cell progenitors and their differentiation to the IgM-positive stage of B cell development. Its receptor TSLP-R will bind TSLP in a low-affinity fashion in transfected cells, co-transfection with IL-7R-alpha cDNA results in high-affinity binding and a functional heteromeric complex. This heteromeric receptor requires stat5 for TSLP-mediated signal transduction and is inhibited by SOCS-1. Despite its predicted molecular weight, TSLP-R often migrates at a higher molecular weight in SDS-PAGE.Synonyms: Cytokine receptor-like 2, Cytokine receptor-like factor 2, IL-XR, ILXR, TSLPR, Thymic stromal lymphopoietin protein receptor

    基因ID

    64109

    UniProt

    Q9HC73
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