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TRIM25 抗体 (N-Term)

This anti-TRIM25 antibody is a 兔 多克隆 antibody detecting TRIM25 in WB, IF 和 EIA. Suitable for 人.
产品编号 ABIN501046
发货至: 中国

Quick Overview for TRIM25 抗体 (N-Term) (ABIN501046)

抗原

See all TRIM25 抗体
TRIM25 (Tripartite Motif Containing 25 (TRIM25))

适用

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宿主

  • 85
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克隆类型

  • 82
  • 9
多克隆

标记

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This TRIM25 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 15
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    • 2
    • 1
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    N-Term

    特异性

    This antibody detects TRIM25 / RNF147 at N-term.

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Peptide affinity chromatography

    免疫原

    TRIM25 antibody was raised against a 15 amino acid peptide from near the amino terminus of human TRIM25.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot. Immunoflourescence.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    TRIM25 (Tripartite Motif Containing 25 (TRIM25))

    别名

    TRIM25 / RNF147

    背景

    TRIM25, also known as estrogen responsive finger protein (EFP) is a member of the RING finger-B box-coiled coil family and is a downstream target of estrogen receptor a. Mice lacking this gene displayed an underdeveloped uterus and reduced estrogen responsiveness demonstrating that this protein is essential for estrogen dependent proliferation. TRIM25 expression is increased in breast carcinoma where it promotes the growth of breast tumor by functioning as an E3 ubiquitin ligase that targets the negative cell cycle checkpoint 14-3-3s. Recent reports have indicated that TRIM25 E3 ubiquitin ligase is essential for the retinoic-acid-inducible gene 1 (RIG-1) signaling pathway to elicit host antiviral innate immunity.Synonyms: EFP, Estrogen-responsive finger protein, RING finger protein 147, Tripartite motif-containing protein 25, ZNF147, Zinc finger protein 147

    基因ID

    7706

    NCBI登录号

    NP_005073
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