Seladin 1 抗体 (AbBy Fluor® 750)
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北京 101111
Quick Overview for Seladin 1 抗体 (AbBy Fluor® 750) (ABIN5010339)
抗原
See all Seladin 1 (DHCR24) 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 小鼠, Pig, 大鼠
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预测反应
- Human,Dog,Cow,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Seladin 1
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亚型
- IgG
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anti-24-Dehydrocholesterol Reductase (DHCR24) antibody
DHCR24 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (AA 227-516) antibodyDHCR24 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (N-Term) antibodyDHCR24 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (AA 1-516) antibodyDHCR24 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (AA 1-516) antibodyDHCR24 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) antibodyDHCR24 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (AA 431-480) antibodyDHCR24 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 猴, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (AA 38-87) antibodyDHCR24 适用: 人, 小鼠, 大鼠, Cow, 兔, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (N-Term) antibodyDHCR24 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-24-Dehydrocholesterol Reductase (DHCR24) (AA 57-87), (N-Term) antibodyDHCR24 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal RB17628 unconjugated
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应用备注
- IF(IHC-P) 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))
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别名
- Seladin 1
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背景
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Synonyms: Seladin1, Seladin-1, DHCR24, 24 dehydrocholesterol reductase, 3-beta-hydroxysterol delta-24-reductase, DCE, Desmosterol to cholesterol enzyme, Diminuto dwarf1 homolog, SELADIN1, Selective AD indicator 1, Selective Alzheimer's Disease Indicator 1.
Background: Seladin 1 is highly expressed in brain, adrenal tissues and adrenal tumours, where this enzyme catalyzes the reduction of the delta-24 double bond of sterol intermediates such as desmosterol, during cholesterol biosynthesis. In addition, Seladin 1 has an anti-apoptotic function by reducing caspase 3 activity during oxidative stress-induced apoptosis and protecting cells against amyloid-beta peptide-induced apoptosis. Several studies have identified a reduction in expression levels of this enzyme in brain regions affected by Alzheimer's disease (hippocampus and the subventricular zone).
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基因ID
- 1718
抗原
-
