FAIM3 抗体 (C-Term)
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Quick Overview for FAIM3 抗体 (C-Term) (ABIN501016)
抗原
See all FAIM3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects FAIM3 / TOSO.
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交叉反应 （详细）
- Species reactivity (tested):Human
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纯化方法
- Affinity chromatography
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免疫原
- Toso antibody was raised against a 13 amino acid peptide from near the carboxy terminus of human Toso.
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亚型
- IgG
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anti-Fas Apoptotic Inhibitory Molecule 3 (FAIM3) (AA 1-390) antibody
FAIM3 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Fas Apoptotic Inhibitory Molecule 3 (FAIM3) (AA 124-223) antibodyFAIM3 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E4 unconjugated
anti-Fas Apoptotic Inhibitory Molecule 3 (FAIM3) (AA 51-150) antibodyFAIM3 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-Fas Apoptotic Inhibitory Molecule 3 (FAIM3) (C-Term) antibodyFAIM3 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Fas Apoptotic Inhibitory Molecule 3 (FAIM3) (AA 1-390) antibodyFAIM3 适用: 人 WB, IHC (p) 宿主: 小鼠 Polyclonal unconjugated
anti-Fas Apoptotic Inhibitory Molecule 3 (FAIM3) (AA 18-251) antibodyFAIM3 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Fas Apoptotic Inhibitory Molecule 3 (FAIM3) (AA 18-262), (Fc Region) antibodyFAIM3 适用: 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fas Apoptotic Inhibitory Molecule 3 (FAIM3) (AA 18-251) antibodyFAIM3 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fas Apoptotic Inhibitory Molecule 3 (FAIM3) (Internal Region) antibodyFAIM3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 1 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- FAIM3 (Fas Apoptotic Inhibitory Molecule 3 (FAIM3))
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别名
- FAIM3 / TOSO
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背景
- Apoptosis is an important process by which normal tissue homeostasis and function are maintained. One of the major signals that regulate this process is mediated by the activation of the Fas receptor by its ligand. This leads to the formation of a Fas-associated death domain (FADD)- containing death-inducing signaling complex and the activation of caspase-8, which in turn activates downstream effector caspases, such as caspase-3 and -7. Recent experiments have shown that overexpression of Toso, a novel regulator of Fas-induced apoptosis in lymphoid cells, in Jurkat cells as well as transgenic mice render these cells resistant to Fas-induced apoptosis but not to TRAIL-induced apoptosis. Furthermore, Toso was found to associate with FADD, suggesting that Toso functions by disrupting the formation of the death-inducing signaling complex. Despite its predicted molecular weight, Toso often migrates at 60 kDa in SDS-PAGE.Synonyms: Fas apoptotic inhibitory molecule 3, Regulator of Fas-induced apoptosis Toso
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基因ID
- 9214
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NCBI登录号
- NP_005440
抗原
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