FNBP1L 抗体 (C-Term)
This anti-FNBP1L antibody is a 兔 多克隆 antibody detecting FNBP1L in WB, IHC (p) 和 EIA. Suitable for 人, 小鼠 和 大鼠.
Quick Overview for FNBP1L 抗体 (C-Term) (ABIN501002)
抗原
See all FNBP1L 抗体
FNBP1L
(Formin Binding Protein 1-Like (FNBP1L))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This FNBP1L antibody is un-conjugated
应用范围
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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抗原表位
- C-Term
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特异性
- This antibody detects FNBP1L at C-term.
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交叉反应 （详细）
- Species reactivity (tested):Huuman, mouse, rat
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纯化方法
- Peptide affinity chromatography
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免疫原
- TOCA-1 antibody was raised against a 17 amino acid peptide near the carboxy terminus of the human TOCA-1.
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亚型
- IgG
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anti-Formin Binding Protein 1-Like (FNBP1L) (AA 175-239) antibody
FNBP1L 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 1E6 unconjugated
anti-Formin Binding Protein 1-Like (FNBP1L) (N-Term) antibodyFNBP1L 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- FNBP1L (Formin Binding Protein 1-Like (FNBP1L))
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别名
- FNBP1L
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背景
- Actin reorganization is important for the regulation of neuronal morphology. A protein involved in this process, the transducer of cdc42-dependent actin assembly 1 (TOCA-1) protein, a member of the evolutionarily conserved pombe CDC15 homology (PCH) protein family, is an essential component of the Cdc42 pathway. TOCA-1 binds both N-WASP and Cdc42 and is essential for Cdc42- and PIP2-induced actin polymerization, suggesting that TOCA-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex. Decreased expression of TOCA-1 significantly enhances neurite elongation in PC-12 cells, its overexpression in the same cells suppresses neurite elongation. It has been suggested that TOCA-1 negatively regulates axon branching by regulating membrane trafficking by regulating membrane trafficking through the F-BAR/EFC domain. Multiple isoforms of TOCA-1 are known to exist.Synonyms: C1orf39, Formin-binding protein 1-like, TOCA1, Transducer of Cdc42-dependent actin assembly protein 1
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基因ID
- 54874
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NCBI登录号
- NP_001020119
抗原
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