TRIM11 抗体 (AbBy Fluor® 750)
Quick Overview for TRIM11 抗体 (AbBy Fluor® 750) (ABIN5010004)
抗原
See all TRIM11 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human TRIM11/RNF92
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亚型
- IgG
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anti-Tripartite Motif Containing 11 (TRIM11) (AA 267-468) antibody
TRIM11 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 11 (TRIM11) (AA 383-432) antibodyTRIM11 适用: 人, 小鼠, 大鼠, 马 WB 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 11 (TRIM11) (AA 249-263) antibodyVerified TRIM11 适用: 人 ELISA, WB, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Tripartite Motif Containing 11 (TRIM11) (C-Term) antibodyVerified TRIM11 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Tripartite Motif Containing 11 (TRIM11) (AA 267-468) antibodyTRIM11 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Tripartite Motif Containing 11 (TRIM11) (AA 300-329), (C-Term) antibodyTRIM11 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB33239 unconjugated
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应用备注
- IF(IHC-P) 1:50-200
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- TRIM11 (Tripartite Motif Containing 11 (TRIM11))
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别名
- RNF92
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背景
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Synonyms: BIA 1, E3 ubiquitin protein ligase TRIM11, E3 ubiquitin-protein ligase TRIM11, Protein BIA1, RING finger protein 92, RNF 92, TRI11_HUMAN, Trim 11, TRIM11, Tripartite mot containing 11, tripartite mot protein 11, Tripartite mot-containing protein 11.
Background: E3 ubiquitin-protein ligase that promotes the degradation of insoluble ubiquitinated proteins, including insoluble PAX6, poly-Gln repeat expanded HTT and poly-Ala repeat expanded ARX. Mediates PAX6 ubiquitination leading to proteasomal degradation, thereby modulating cortical neurogenesis. May also inhibit PAX6 transcriptional activity, possibly in part by preventing the binding of PAX6 to its consensus sequences. May contribute to the regulation of the intracellular level of HN (humanin) or HN-containing proteins through the proteasomal degradation pathway. Mediates MED15 ubiquitination leading to proteasomal degradation. May contribute to the innate restriction of retroviruses. Upon overexpression, reduces HIV-1 and murine leukemia virus infectivity, by suppressing viral gene expression. Antiviral activity depends on a functional E3 ubiquitin-protein ligase domain. May regulate TRIM5 turnover via the proteasome pathway, thus counteracting the TRIM5-mediated cross-species restriction of retroviral infection at early stages of the retroviral life cycle.
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基因ID
- 81559
抗原
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