TLR11 抗体 (C-Term, Middle Region)
Our Local Distributor
北京 101111
Quick Overview for TLR11 抗体 (C-Term, Middle Region) (ABIN500944)
抗原
See all TLR11 (Tlr11) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term, Middle Region
-
交叉反应 (详细)
- Species reactivity (tested):Mouse
-
纯化方法
- Ion exchange chromatography
-
免疫原
- TLR11 antibody was raised against a peptide corresponding to 16 amino acids between the middle and carboxy terminus of mouse TLR11 (GenBank accession no NP_991388).
-
亚型
- IgG
-
-
-
-
应用备注
-
ELISA. Western blot: 0.5 to 2 μg/mL. Imunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- PBS containing 0.02 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- -20 °C
-
储存方法
- Store the antibody (in aliquots) at -20 °C.
-
-
- TLR11 (Tlr11) (Toll-Like Receptor 11 (Tlr11))
-
别名
- TLR11
-
背景
- Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5). TLR11 is one of three mouse TLRs that lack a human ortholog (6). It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system (7).Synonyms: Gm287, Toll-like receptor 11
-
基因ID
- 239081
-
NCBI登录号
- NP_991388
-
途径
- Activation of Innate immune Response
抗原
-