TLR11 抗体 (C-Term)
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Quick Overview for TLR11 抗体 (C-Term) (ABIN500942)
抗原
See all TLR11 (Tlr11) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects TLR11 at C-term.
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交叉反应 (详细)
- Species reactivity (tested):Mouse
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纯化方法
- Ion exchange chromatography
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免疫原
- TLR11 antibody was raised against a peptide corresponding to 15 amino acids near the carboxy-terminus of mouse TLR11.
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亚型
- IgG
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应用备注
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ELISA. Western blot: 0.5 to 1 μg/mL. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- TLR11 (Tlr11) (Toll-Like Receptor 11 (Tlr11))
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别名
- TLR11
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背景
- Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors (4,5). TLR11 is one of three mouse TLRs that lack a human ortholog (6). It is activated specifically by uropathogenic bacteria, and mice lacking TLR11 showed a much greater susceptability to uropathogenic infections, indicating a potentially important role for TLR11 in preventing infections in the urogenital system (7).Synonyms: Gm287, Toll-like receptor 11
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基因ID
- 239081
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NCBI登录号
- NP_991388
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途径
- Activation of Innate immune Response
抗原
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