PRNP 抗体 (AA 23-120) (AbBy Fluor® 750)
Quick Overview for PRNP 抗体 (AA 23-120) (AbBy Fluor® 750) (ABIN5009163)
抗原
See all PRNP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 23-120
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预测反应
- Human,Mouse,Rat,Cow,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human PRNP
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- PRNP (Prion Protein (PRNP))
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别名
- Prion protein PrP/CD230
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背景
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Synonyms: AltPrP, ASCR, atal familial insomnia, CD230, CD230 antigen, CJD, Creutzfeld Jakob disease, Gerstmann-Strausler-Scheinker syndrome, GSS, KURU, Major prion protein, PRIO_HUMAN.
Background: The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).
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基因ID
- 5621
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UniProt
- P04156
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途径
- Transition Metal Ion Homeostasis, Activated T Cell Proliferation
抗原
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