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PRNP 抗体 (AA 51-150) (AbBy Fluor® 750)

This AbBy Fluor® 750-conjugated 兔 多克隆 anti-PRNP antibody specifically detects PRNP in IF (cc) 和 IF (p). The antibody is reactive with 人 samples.
产品编号 ABIN5009161
发货至: 中国
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Quick Overview for PRNP 抗体 (AA 51-150) (AbBy Fluor® 750) (ABIN5009161)

抗原

See all PRNP 抗体
PRNP (Prion Protein (PRNP))

适用

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宿主

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克隆类型

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多克隆

标记

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This PRNP antibody is conjugated to AbBy Fluor® 750

应用范围

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Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 15
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    AA 51-150

    预测反应

    Human,Mouse,Rat,Cow,Sheep,Horse

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human PRNP

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    PRNP (Prion Protein (PRNP))

    别名

    Prion protein PrP

    背景

    Synonyms: AltPrP, ASCR, atal familial insomnia, CD230, CD230 antigen, CJD, Creutzfeld Jakob disease, Gerstmann-Strausler-Scheinker syndrome, GSS, KURU, Major prion protein, MGC26679, p27 30, PRIO_HUMAN, Prion protein, Prion related protein, PRIP, Prni, Prnp, PrP, PrP27 30, PrP27-30, PrP33 35C, PrP33-35C, PrPC, PrPSc, Sinc.

    Background: The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012].

    基因ID

    5621

    UniProt

    P04156

    途径

    Transition Metal Ion Homeostasis, Activated T Cell Proliferation
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