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HAVCR1 抗体 (N-Term)

This anti-HAVCR1 antibody is a 兔 多克隆 antibody detecting HAVCR1 in WB, IHC (p) 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN500911
发货至: 中国

Quick Overview for HAVCR1 抗体 (N-Term) (ABIN500911)

抗原

See all HAVCR1 抗体
HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))

适用

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人, 小鼠

宿主

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克隆类型

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多克隆

标记

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This HAVCR1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    N-Term

    特异性

    This antibody detects TIMD1 / HAVCR1 at N-term.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse

    纯化方法

    Peptide affinity chromatography

    免疫原

    TIM-1 antibody was raised against a 16 amino acid peptide from near the amino terminus of human TIM-1.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))

    别名

    TIMD1 / HAVCR1

    物质类

    Virus

    背景

    The human form of TIM-1 was initially discovered as a membrane glycoprotein through which the hepatitis A virus can gain entry into a cell. It was also identified as kidney injury molecule 1 (Kim-1), a predicted adhesion molecule that is upregulated on the surfaces of kidney epithelia. It is also expressed on T helper 2 (Th2) cells of the immune system, and following the binding of its natural ligand TIM-4, stimulates T cell expansion and cytokine production in response to viral challenge. It has been suggested that hyperactivation of TIM-1 leads to an increased level of Th2 responsiveness and asthma susceptibility, and antibodies to TIM-1 may therefore be a novel approach to treating asthma.Synonyms: HAVCR-1, Hepatitis A virus cellular receptor 1, T cell immunoglobulin and mucin domain-containing protein 1, T cell membrane protein 1, TIM-1, TIM1, TIMD-1

    基因ID

    26762

    NCBI登录号

    NP_036338
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