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GPR124 抗体 (Center)

This anti-GPR124 antibody is a 兔 多克隆 antibody detecting GPR124 in WB, IHC (p) 和 EIA. Suitable for 人 和 大鼠.
产品编号 ABIN500897
发货至: 中国

Quick Overview for GPR124 抗体 (Center) (ABIN500897)

抗原

See all GPR124 抗体
GPR124 (G Protein-Coupled Receptor 124 (GPR124))

适用

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人, 大鼠

宿主

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克隆类型

  • 46
多克隆

标记

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This GPR124 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    Center

    特异性

    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.

    交叉反应 (详细)

    Species reactivity (tested):Human, rat

    纯化方法

    Peptide affinity chromatography

    免疫原

    TEM5 antibody was raised against a 14 amino acid peptide near the center of human TEM5.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    GPR124 (G Protein-Coupled Receptor 124 (GPR124))

    别名

    GPR124 / TEM5

    背景

    Tumor endothelial markers (TEMs) are significantly up-regulated during angiogenesis and neoangiogensis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies. These include TEMs such as TEM1, TEM5, TEM7 and TEM8. TEM5 is a member of the adhesion family of G protein coupled receptors and is localized on the surface of endothelial cells. TEM5 is a seven-pass transmembrane receptor, unlike TEM1, TEM7 and TEM8 which span the membrane once. TEM5 is abundantly expressed in tumor vessels, heart, placenta, ovary, small intestine, and colon. Proteolytically processed soluble TEM5 mediates endothelial cell survival during angiogenesis by linking integrin to glycosaminoglycans.Synonyms: G-protein coupled receptor 124, KIAA1531, Tumor endothelial marker 5

    基因ID

    25960

    UniProt

    Q96PE1
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