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RASD2 抗体 (C-Term)

This anti-RASD2 antibody is a 兔 多克隆 antibody detecting RASD2 in WB, IHC (p) 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN500889
发货至: 中国

Quick Overview for RASD2 抗体 (C-Term) (ABIN500889)

抗原

See all RASD2 抗体
RASD2 (RASD Family, Member 2 (RASD2))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This RASD2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    C-Term

    特异性

    This antibody detects RASD2 / TEM2 at C-term.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Peptide affinity chromatography

    免疫原

    TEM2 antibody was raised against a 15 amino acid peptide near the carboxy terminus of the human TEM2.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    RASD2 (RASD Family, Member 2 (RASD2))

    别名

    RASD2 / TEM2

    背景

    Rhes, also known as tumor endothelial marker 2 (TEM2), is a small GTP-binding protein that is predominantly expressed in the striatal region of the brain. This protein belongs to the RASD subfamily of Ras-related GTP-binding protein superfamily and is thought to play a role in the normal development and function of the brain as mice lacking this gene showed increased anxiety levels and motor coordination deficits. Rhes was identified as TEM2 through analysis of genes whose expression was upregulated in tumor endothelium. Tumor endothelial markers are significantly up-regulated during angiogenesis and neoangiogenesis that are crucial for the growth of solid tumors. TEMs localized on the cell surface and conserved across species are of particular interest for future development of anti-angiogenic therapies.Synonyms: GTP-binding protein Rhes, Ras homolog enriched in striatum, Tumor endothelial marker 2

    基因ID

    23551

    UniProt

    Q96D21
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