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CD248 抗体 (N-Term)

CD248 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500887
发货至: 中国
  • 抗原 See all CD248 抗体
    CD248 (CD248 Molecule, Endosialin (CD248))
    抗原表位
    • 16
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 43
    • 32
    • 13
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 39
    • 5
    • 1
    克隆类型
    • 41
    • 4
    多克隆
    标记
    • 26
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CD248 antibody is un-conjugated
    应用范围
    • 44
    • 20
    • 15
    • 13
    • 13
    • 9
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects CD248 / TEM1 at N-term. It recognizes only the larger isoform.
    交叉反应 (详细)
    Species reactivity (tested):Human, Mouse, Rat
    纯化方法
    Peptide Affinity Chromatography
    免疫原
    A 14 amino acid peptide near the amino terminus of the Human TEM1.
    亚型
    IgG
    Top Product
    Discover our top product CD248 Primary Antibody
  • 应用备注
    ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS, 0.02 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原
    CD248 (CD248 Molecule, Endosialin (CD248))
    别名
    CD248 / TEM1 (CD248 产品)
    别名
    CD164L1 antibody, TEM1 antibody, 2610111G01Rik antibody, AI842296 antibody, Cd164l1 antibody, Tem1 antibody, fb96b12 antibody, wu:fb96b12 antibody, zgc:162651 antibody, CD248 molecule antibody, CD248 antigen, endosialin antibody, CD248 molecule, endosialin a antibody, CD248 antibody, Cd248 antibody, cd248a antibody
    背景
    Tumor endothelial marker (TEM) 1 was originally identified as a human embryonic fibroblast-specific antigen and was later determined to be endosialin, a single-pass transmembrane glycoprotein that has multiple extracellular domains, including three EGF-like domains, a sushi-like domain, and a C lectin-like domain. TEM proteins are significantly up-regulated during angiogenesis and neoangiogenesis that are crucial for the growth of solid tumors. While TEM1 is not required for angiogenesis during fetal development, postnatal growth or wound healing, it plays a role in tumor growth, invasion, and metastasis. Fibronectin and collagen types I and IV act as specific ligands of TEM1, leading to suggestions that these molecules may cause changes in the extracellular matrix, cell adhesion and migration during tumor invasion. At least two isoforms of TEM1 are known to exist.Synonyms: CD164L1, Endosialin, Tumor endothelial marker 1
    基因ID
    57124
    NCBI登录号
    NP_065137
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