CD248 抗体 (C-Term)
Quick Overview for CD248 抗体 (C-Term) (ABIN500885)
抗原
See all CD248 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects CD248 / TEM1 at C-term. It recognizes both isoforms.
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse, Rat
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纯化方法
- Peptide affinity chromatography
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免疫原
- TEM1 antibody was raised against a 14 amino acid peptide near the carboxy terminus of the human TEM1.
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亚型
- IgG
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anti-CD248 Molecule, Endosialin (CD248) (AA 251-350) antibody
CD248 适用: 人, 小鼠 WB, ELISA, FACS, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-CD248 Molecule, Endosialin (CD248) (AA 18-180) antibodyCD248 适用: 人 ELISA, FACS 宿主: 小鼠 Monoclonal 1H11A10 unconjugated
anti-CD248 Molecule, Endosialin (CD248) (AA 18-757) antibodyCD248 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2A7 unconjugated
anti-CD248 Molecule, Endosialin (CD248) (C-Term) antibodyCD248 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-CD248 Molecule, Endosialin (CD248) (AA 18-150) antibodyCD248 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CD248 Molecule, Endosialin (CD248) (C-Term) antibodyCD248 适用: 人, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-CD248 Molecule, Endosialin (CD248) (N-Term) antibodyCD248 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-CD248 Molecule, Endosialin (CD248) (AA 1-757) antibodyCD248 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-CD248 Molecule, Endosialin (CD248) (AA 1-757) antibodyCD248 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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应用备注
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ELISA. Western blot. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS, 0.02 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- CD248 (CD248 Molecule, Endosialin (CD248))
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别名
- CD248 / TEM1
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背景
- Tumor endothelial marker (TEM) 1 was originally identified as a human embryonic fibroblast-specific antigen and was later determined to be endosialin, a single-pass transmembrane glycoprotein that has multiple extracellular domains, including three EGF-like domains, a sushi-like domain, and a C lectin-like domain. TEM proteins are significantly up-regulated during angiogenesis and neoangiogenesis that are crucial for the growth of solid tumors. While TEM1 is not required for angiogenesis during fetal development, postnatal growth or wound healing, it plays a role in tumor growth, invasion, and metastasis. Fibronectin and collagen types I and IV act as specific ligands of TEM1, leading to suggestions that these molecules may cause changes in the extracellular matrix, cell adhesion and migration during tumor invasion. At least two isoforms of TEM1 are known to exist.Synonyms: CD164L1, Endosialin, Tumor endothelial marker 1
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基因ID
- 57124
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NCBI登录号
- NP_065137
抗原
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