DCAF12 抗体 (C-Term)
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北京 101111
Quick Overview for DCAF12 抗体 (C-Term) (ABIN500873)
抗原
See all DCAF12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects DCAF12.
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纯化方法
- Peptide affinity chromatography
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免疫原
- TCC52 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human TCC52.
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亚型
- IgG
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应用备注
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ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- DCAF12 (DDB1 and CUL4 Associated Factor 12 (DCAF12))
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别名
- DCAF12
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背景
- Cancer-testis (CT) antigens are a type of antigen whose expression is highly restricted, primarily in normal testis, but aberrantly in different tumor types. Their immunogenicity in cancer patients makes them prime targets for immunotherapy of human tumors. One such CT antigen is TCC52, a novel centrosomal protein. TCC52 is a WD repeat-containing protein that interacts with the COP9 signalosome, a macromolecular complex that interacts with cullin-RING E3 ligases and regulates their activity by hydrolyzing cullin-Nedd8 conjugates. The normal biological function of this protein is not known at this time.Synonyms: Centrosome-related protein TCC52, DDB1- and CUL4-associated factor 12, KIAA1892, TCC52, Testis cancer centrosome-related protein, WD repeat-containing protein 40A, WDR40A
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基因ID
- 25853
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NCBI登录号
- NP_056212
抗原
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