SYPL2 抗体 (C-Term)
This 兔 多克隆 antibody specifically detects SYPL2 in WB, IHC (p) 和 EIA. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN500857
发货至:
中国
Contact our Customer Service for availability and price in your country.
Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for SYPL2 抗体 (C-Term) (ABIN500857)
抗原
See all SYPL2 抗体
SYPL2
(Synaptophysin-Like 2 (SYPL2))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This SYPL2 antibody is un-conjugated
应用范围
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
-
-
抗原表位
- C-Term
-
特异性
- This antibody detects SYPL2. It will not cross-react with SYPL1.
-
交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
-
纯化方法
- Peptide affinity chromatography
-
免疫原
- SYPL2 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human SYPL.
-
亚型
- IgG
-
-
-
-
应用备注
-
ELISA. Western blot. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
缓冲液
- PBS containing 0.02 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
-
-
- SYPL2 (Synaptophysin-Like 2 (SYPL2))
-
别名
- SYPL2
-
背景
- SYPL2, also known as Mitsugumin 29, was initially identified as a transmembrane protein from the triad junction in skeletal muscle that had significant homology with members of the synaptophysin family. SYPL2 is thought to participate in the excitation-contraction coupling process of skeletal muscle as SYPL2-null mice showed reduced muscle contractile force and altered triad junction structure and increased susceptibility to fatigue of the skeletal muscle. SYPL2 plays a critical role in muscle Ca2+ signaling by regulating the process of store-operated Ca2+ entry and interacts with ryanodine receptor (RyR), thereby influencing intracellular Ca2+ homeostasis through changes in the RyR/Ca2+ release function. Co-expression of SYPL2 and RyR in cultured cells leads to apoptotic cell death resulting from the depletion of Ca2+ from the intracellular stores. At least two isoforms of SYPL2 are known to exist.Synonyms: Synaptophysin-like protein 2
-
基因ID
- 284612
-
NCBI登录号
- NP_001035799
抗原
-
You are here:
