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Stim2 抗体 (Center)

Stim2 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500831
发货至: 中国
  • 抗原 See all Stim2 抗体
    Stim2 (Stromal Interaction Molecule 2 (Stim2))
    抗原表位
    • 10
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    适用
    • 38
    • 14
    • 9
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 36
    • 1
    • 1
    克隆类型
    • 38
    多克隆
    标记
    • 22
    • 5
    • 4
    • 3
    • 2
    • 2
    This Stim2 antibody is un-conjugated
    应用范围
    • 34
    • 27
    • 19
    • 5
    • 4
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects STIM2 at center. It is predicted to have no cross-reactivity to STIM1.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Peptide affinity chromatography
    免疫原
    STIM2 antibody was raised against a 17 amino acid peptide from near the center of human STIM2.
    亚型
    IgG
    Top Product
    Discover our top product Stim2 Primary Antibody
  • 应用备注
    ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    Stim2 (Stromal Interaction Molecule 2 (Stim2))
    别名
    STIM2 (Stim2 产品)
    别名
    STIM2 antibody, stromal interaction molecule 2 antibody, STIM2 antibody, stim2 antibody, Stim2 antibody
    背景
    In T lymphocytes, the sole pathway for Ca++ entry following antigen-receptor binding is through store-operated Ca++-release-activated Ca++ (CRAC) channels. These channels are made up of the pore-forming subunit ORAI1 and the stromal interaction molecule 1 (STIM1), a protein that functions as a Ca++ sensor and activates the CRAC channels, migrating to the plasma membrane from endoplasmic reticulum (ER)-like sites which act as the Ca++ store. A related molecule, STIM2, acts to inhibit the STIM1-mediated store-operated Ca++ entry, and can form complexes with STIM1, suggesting they may play a coordinated role in controlling Ca++ entry. At least three isoforms of STIM2 are known to exist. This STIM2 antibody is predicted to have no cross-reactivity to STIM1.Synonyms: KIAA1482, Stromal interaction molecule 2
    基因ID
    57620
    NCBI登录号
    NP_065911
    途径
    TCR Signaling, BCR Signaling
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