STEAP3 抗体 (N-Term)
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北京 101111
Quick Overview for STEAP3 抗体 (N-Term) (ABIN500823)
抗原
See all STEAP3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects STEAP3 / TSAP6. It does not cross-react with other STEAP proteins.
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交叉反应 (详细)
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Peptide affinity chromatography
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免疫原
- STEAP3 antibody was raised against a 15 amino acid peptide from near the amino terminus of human STEAP3.
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亚型
- IgG
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应用备注
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ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- STEAP3 (STEAP Family Member 3, Metalloreductase (STEAP3))
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别名
- STEAP3 / TSAP6
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背景
- The six-transmembrane epithelial antigen of prostate 3 (STEAP3) is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. Similar to two other members of the STEAP family (STEAP 2 and STEAP4), STEAP3 promotes both iron and copper reduction. STEAP3 is highly expressed in hematopoietic tissues and colocalizes with the transferrin endosome. Overexpression of STEAP3 stimulates iron reduction, mice lacking STEAP3 are deficient in erythroid ferrireductase activity, suggesting that STEAP3 is an endosomal ferrireductase required for transferrin-dependent iron uptake in erythroid cells.Synonyms: Dudulin-2, Metalloreductase STEAP3, STEAP-3, Six-transmembrane epithelial antigen of prostate 3, Tumor suppressor-activated pathway protein 6, pH yde
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基因ID
- 55240
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途径
- Transition Metal Ion Homeostasis
抗原
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