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IL1RL1 抗体 (N-Term)

This anti-IL1RL1 antibody is a 兔 多克隆 antibody detecting IL1RL1 in WB, IHC (p) 和 EIA. Suitable for 人 和 小鼠.
产品编号 ABIN500811
发货至: 中国

Quick Overview for IL1RL1 抗体 (N-Term) (ABIN500811)

抗原

See all IL1RL1 抗体
IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))

适用

  • 60
  • 9
  • 2
  • 2
  • 1
人, 小鼠

宿主

  • 41
  • 15
  • 4
  • 1
  • 1
  • 1

克隆类型

  • 43
  • 20
多克隆

标记

  • 43
  • 6
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This IL1RL1 antibody is un-conjugated

应用范围

  • 43
  • 23
  • 16
  • 14
  • 6
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

    • 10
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    特异性

    This antibody detects ST2 at N-term.

    交叉反应 (详细)

    Species reactivity (tested):Human, Mouse.

    纯化方法

    Peptide Affinity Chromatography

    免疫原

    A synthetic peptide corresponding to 16 amino acids at the amino-terminus of Mouse ST2. Remarks: This peptide is common to all three known ST2 isoforms.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 1-2 μg/mL. Immunohistochemistry on Paraffin Sections. Positive Control: Mouse Kidney Tissue Lysate.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS, 0.02 % Sodium Azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • 抗原

    IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))

    别名

    IL1RL1 / ST2

    背景

    ST2 is a member of a superfamily containing the interleukin-1 receptor and the Toll-like receptors (TLRs). The TLRs are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1,2). ST2 was originally identified as a protein whose production was stimulated by various proliferation-inducing agents such as PDGF and FGF (3). More recently, it has been shown to negatively regulate IL-1 receptor and Toll-like receptor (TLR) 4 signaling and to maintain endotoxin tolerance (4,5). It has been suggested that the inhibition of TLR4 signaling occurs through the association and sequestering of TLR adaptor molecules such as MyD88 and TIRAP (6).Synonyms: DER4, FIT-1, Homolog of mouse growth stimulation-expressed, Interleukin-1 receptor-like 1, MGC32623

    基因ID

    9173

    NCBI登录号

    NP_003847
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