IL1RL1 抗体 (N-Term)
Our Local Distributor
北京 101111
Quick Overview for IL1RL1 抗体 (N-Term) (ABIN500811)
抗原
See all IL1RL1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- N-Term
-
特异性
- This antibody detects ST2 at N-term.
-
交叉反应 (详细)
- Species reactivity (tested):Human, Mouse.
-
纯化方法
- Peptide Affinity Chromatography
-
免疫原
- A synthetic peptide corresponding to 16 amino acids at the amino-terminus of Mouse ST2. Remarks: This peptide is common to all three known ST2 isoforms.
-
亚型
- IgG
-
-
-
-
应用备注
-
ELISA. Western blot: 1-2 μg/mL. Immunohistochemistry on Paraffin Sections. Positive Control: Mouse Kidney Tissue Lysate.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
浓度
- 1.0 mg/mL
-
缓冲液
- PBS, 0.02 % Sodium Azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- IL1RL1 (Interleukin 1 Receptor-Like 1 (IL1RL1))
-
别名
- IL1RL1 / ST2
-
背景
- ST2 is a member of a superfamily containing the interleukin-1 receptor and the Toll-like receptors (TLRs). The TLRs are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1,2). ST2 was originally identified as a protein whose production was stimulated by various proliferation-inducing agents such as PDGF and FGF (3). More recently, it has been shown to negatively regulate IL-1 receptor and Toll-like receptor (TLR) 4 signaling and to maintain endotoxin tolerance (4,5). It has been suggested that the inhibition of TLR4 signaling occurs through the association and sequestering of TLR adaptor molecules such as MyD88 and TIRAP (6).Synonyms: DER4, FIT-1, Homolog of mouse growth stimulation-expressed, Interleukin-1 receptor-like 1, MGC32623
-
基因ID
- 9173
-
NCBI登录号
- NP_003847
抗原
-