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SRPX 抗体 (N-Term)

This anti-SRPX antibody is a 兔 多克隆 antibody detecting SRPX in WB, IHC (p) 和 EIA. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN500807
发货至: 中国

Quick Overview for SRPX 抗体 (N-Term) (ABIN500807)

抗原

See all SRPX 抗体
SRPX (Sushi-Repeat Containing Protein, X-Linked (SRPX))

适用

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人, 小鼠, 大鼠

宿主

  • 39
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克隆类型

  • 41
多克隆

标记

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This SRPX antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
  • 抗原表位

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    N-Term

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Peptide affinity chromatography

    免疫原

    SRPX1 antibody was raised against a 13 amino acid peptide from near the amino terminus of human SRPX1.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 0.25 - 0.5 μg/mL. Immunhistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 浓度

    1.0 mg/mL

    缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody (in aliquots) at -20 °C.
  • 抗原

    SRPX (Sushi-Repeat Containing Protein, X-Linked (SRPX))

    别名

    SRPX / ETX1

    背景

    SRPX1 was initially identified as a candidate gene for X-linked retinitis pigmentosa and is overexpressed in the trabecular network of the eye in glaucoma conditions. Its expression is significantly downregulated in a number cancer cell lines and malignant tumor tissues and its ectopic expression induces apoptosis through the endoplasmic reticulum and the activation of caspase-12, -9, and -3, indicating that it can function as a tumor suppressor. SRPX1 is also involved with the regulation of autophagy under low serum conditions and can associate with Rab24, a member of the Rab GTPase protein family that is involved in autophagy. This association of SRPX1 with Rab24 is enhanced during autophagy.Synonyms: Sushi repeat-containing protein SRPX

    基因ID

    8406

    NCBI登录号

    NP_006298
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