SRPX 抗体 (N-Term)
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Quick Overview for SRPX 抗体 (N-Term) (ABIN500807)
抗原
See all SRPX 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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交叉反应 (详细)
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Peptide affinity chromatography
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免疫原
- SRPX1 antibody was raised against a 13 amino acid peptide from near the amino terminus of human SRPX1.
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亚型
- IgG
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应用备注
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ELISA. Western blot: 0.25 - 0.5 μg/mL. Immunhistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- SRPX (Sushi-Repeat Containing Protein, X-Linked (SRPX))
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别名
- SRPX / ETX1
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背景
- SRPX1 was initially identified as a candidate gene for X-linked retinitis pigmentosa and is overexpressed in the trabecular network of the eye in glaucoma conditions. Its expression is significantly downregulated in a number cancer cell lines and malignant tumor tissues and its ectopic expression induces apoptosis through the endoplasmic reticulum and the activation of caspase-12, -9, and -3, indicating that it can function as a tumor suppressor. SRPX1 is also involved with the regulation of autophagy under low serum conditions and can associate with Rab24, a member of the Rab GTPase protein family that is involved in autophagy. This association of SRPX1 with Rab24 is enhanced during autophagy.Synonyms: Sushi repeat-containing protein SRPX
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基因ID
- 8406
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NCBI登录号
- NP_006298
抗原
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