SLC51B 抗体 (AbBy Fluor® 680)
Quick Overview for SLC51B 抗体 (AbBy Fluor® 680) (ABIN5008063)
抗原
See all SLC51B (OSTBETA) 抗体适用
宿主
克隆类型
标记
应用范围
-
-
交叉反应
- 小鼠
-
预测反应
- Human,Rat
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human OST-beta
-
亚型
- IgG
-
-
anti-Organic Solute Transporter beta (OSTBETA) (AA 57-128) antibody
OSTBETA 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- IF(IHC-P) 1:50-200
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
-
储存条件
- -20 °C
-
储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
-
有效期
- 12 months
-
-
- SLC51B (OSTBETA) (Organic Solute Transporter beta (OSTBETA))
-
别名
- OST-beta
-
背景
-
Synonyms: organic solute transporter beta Ostbeta, Organic solute transporter subunit beta, Ostbeta, Ost beta, OST-beta, OSTB, OSTB_HUMAN.
Background: The heteromeric transporter OST Alpha/OST Beta facilitates the transport of bile and other steroid solutes across the basolateral epithelial cell membrane of intestine, liver, testis, kidney and adrenal gland. OST Alpha/OST Beta expression is induced by bile acids through ligand-dependent transactivation of their genes by FXR (Farnesoid X-activated receptor). This genetic regulation suggests that in response to changes in intracellular bile acid levels, bile acids adjust the rate of their own efflux from enterocytes. OST Beta is a 128 amino acid single-pass transmembrane protein that requires OST Alpha to localize to the plasma membrane. Coexpression of OST Alpha and OST Beta is also required to convert the OST Alpha subunit to a mature glycosylated endoglycosidase H-resistant form, suggesting that co-expression facilitates trafficking of OST Alpha through the golgi apparatus. Though widely expressed, OST Beta is present at highest levels in ileum.
-
基因ID
- 123264
-
途径
- Regulation of Carbohydrate Metabolic Process
抗原
-
