SPRED2 抗体 (Center)
Our Local Distributor
北京 101111
Quick Overview for SPRED2 抗体 (Center) (ABIN500800)
抗原
See all SPRED2 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- Center
-
特异性
- This antibody detects SPRED2. It is predicted to have no cross-reactivity to Spred1 or Spred3.
-
交叉反应 (详细)
- Species reactivity (tested):Human
-
纯化方法
- Peptide affinity chromatography
-
免疫原
- Spred2 antibody was raised against a 13 amino acid peptide near the center of the human Spred2.
-
亚型
- IgG
-
-
-
-
应用备注
-
ELISA. Western blot: 1 - 2 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
-
-
-
缓冲液
- PBS containing 0.02 % sodium azide
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freezing and thawing.
-
储存条件
- 4 °C/-20 °C
-
储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
-
-
- SPRED2 (Sprouty-Related, EVH1 Domain Containing 2 (SPRED2))
-
别名
- SPRED2
-
背景
- Spred2 is a member of the Sprouty family, a group of proteins that act as negative regulators during development. Like Spred1, Spred2 acts by suppressing the phosphorylation and activation of Raf. The Spred proteins have also been implicated in the negative feedback regulation of FGF signaling in embryogenesis and angiogenesis. Further studies have shown that expression levels of Spred1 and Spred2 proteins are inversely correlated with the incidence of tumor invasion and metastasis in human hepatocellular carcinoma (HHC), suggesting that these proteins could be useful as prognostic factors and therapeutic targets in HCC. At least two isoforms of Spred2 are known to exist.Synonyms: MGC163164, Spred-2, Sprouty-related EVH1 domain containing 2
-
基因ID
- 200734
-
NCBI登录号
- NP_861449
抗原
-