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SPRED2 抗体 (Center)

This anti-SPRED2 antibody is a 兔 多克隆 antibody detecting SPRED2 in WB 和 EIA. Suitable for 人.
产品编号 ABIN500800
发货至: 中国

Quick Overview for SPRED2 抗体 (Center) (ABIN500800)

抗原

See all SPRED2 抗体
SPRED2 (Sprouty-Related, EVH1 Domain Containing 2 (SPRED2))

适用

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宿主

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克隆类型

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多克隆

标记

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This SPRED2 antibody is un-conjugated

应用范围

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Western Blotting (WB), Enzyme Immunoassay (EIA)
  • 抗原表位

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    Center

    特异性

    This antibody detects SPRED2. It is predicted to have no cross-reactivity to Spred1 or Spred3.

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Peptide affinity chromatography

    免疫原

    Spred2 antibody was raised against a 13 amino acid peptide near the center of the human Spred2.

    亚型

    IgG
  • 应用备注

    ELISA. Western blot: 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    限制

    仅限研究用
  • 缓冲液

    PBS containing 0.02 % sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    4 °C/-20 °C

    储存方法

    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原

    SPRED2 (Sprouty-Related, EVH1 Domain Containing 2 (SPRED2))

    别名

    SPRED2

    背景

    Spred2 is a member of the Sprouty family, a group of proteins that act as negative regulators during development. Like Spred1, Spred2 acts by suppressing the phosphorylation and activation of Raf. The Spred proteins have also been implicated in the negative feedback regulation of FGF signaling in embryogenesis and angiogenesis. Further studies have shown that expression levels of Spred1 and Spred2 proteins are inversely correlated with the incidence of tumor invasion and metastasis in human hepatocellular carcinoma (HHC), suggesting that these proteins could be useful as prognostic factors and therapeutic targets in HCC. At least two isoforms of Spred2 are known to exist.Synonyms: MGC163164, Spred-2, Sprouty-related EVH1 domain containing 2

    基因ID

    200734

    NCBI登录号

    NP_861449
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