SPRED1 抗体 (Center)
Quick Overview for SPRED1 抗体 (Center) (ABIN500796)
抗原
See all SPRED1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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特异性
- This antibody detects SPRED1 at center. It is predicted to have no cross-reactivity to Spred2 or Spred3.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Peptide affinity chromatography
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免疫原
- Spred1 antibody was raised against a 20 amino acid peptide near the center of the human Spred1.
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亚型
- IgG
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anti-Sprouty-Related, EVH1 Domain Containing 1 (SPRED1) (AA 123-311) antibody
SPRED1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Sprouty-Related, EVH1 Domain Containing 1 (SPRED1) antibodySPRED1 适用: 人 WB, IHC, IHC (p), FACS 宿主: 兔 Polyclonal unconjugated
anti-Sprouty-Related, EVH1 Domain Containing 1 (SPRED1) (AA 1-444) antibodySPRED1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Sprouty-Related, EVH1 Domain Containing 1 (SPRED1) (Middle Region 2) antibodySPRED1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sprouty-Related, EVH1 Domain Containing 1 (SPRED1) (Middle Region 1) antibodySPRED1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Sprouty-Related, EVH1 Domain Containing 1 (SPRED1) (N-Term) antibodySPRED1 适用: 人 WB, EIA 宿主: 兔 Polyclonal unconjugated
anti-Sprouty-Related, EVH1 Domain Containing 1 (SPRED1) (C-Term) antibodySPRED1 适用: 人 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- SPRED1 (Sprouty-Related, EVH1 Domain Containing 1 (SPRED1))
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别名
- SPRED1
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背景
- The Ras-MAP kinase pathway is essential for the differentiation of neuronal cells and myocytes, it is inhibited by Spred1, a member of the Sprouty family of proteins. Spred1 acts by suppressing the phosphorylation and activation of Raf. The Spred proteins have also been implicated in the negative feedback regulation of FGF signaling in embryogenesis and angiogenesis. Further studies have shown that expression levels of Spred1 and Spred2 proteins are inversely correlated with the incidence of tumor invasion and metastasis in human hepatocellular carcinoma (HHC), suggesting that these proteins could be useful as prognostic factors and therapeutic targets in HCC. Defects in this gene are a cause of neurofibromatosis type 1-like syndrome (NFLS).Synonyms: EVH1/Sprouty domain containing protein, NFLS, Spred-1, Suppressor of Ras/MAPK activation
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基因ID
- 161742
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NCBI登录号
- NP_689807
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途径
- Positive Regulation of Response to DNA Damage Stimulus
抗原
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