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SOX2 抗体 (N-Term)

SOX2 适用: 人, 小鼠, 大鼠 WB, EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500792
发货至: 中国
  • 抗原 See all SOX2 抗体
    SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
    抗原表位
    • 17
    • 16
    • 16
    • 16
    • 15
    • 15
    • 13
    • 11
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    N-Term
    适用
    • 200
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    人, 小鼠, 大鼠
    宿主
    • 163
    • 41
    • 2
    克隆类型
    • 162
    • 44
    多克隆
    标记
    • 100
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    This SOX2 antibody is un-conjugated
    应用范围
    • 162
    • 109
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    Western Blotting (WB), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects SOX2.
    纯化方法
    Peptide affinity chromatography
    免疫原
    SOX2 antibody was raised against a 15 amino acid peptide near the amino terminus of human SOX.
    亚型
    IgG
    Top Product
    Discover our top product SOX2 Primary Antibody
  • 应用备注
    ELISA. Western blot: 1 - 2 μg/mL.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 浓度
    1.0 mg/mL
    缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    -20 °C
    储存方法
    Store the antibody (in aliquots) at -20 °C.
  • 抗原
    SOX2 (SRY (Sex Determining Region Y)-Box 2 (SOX2))
    别名
    SOX2 (SOX2 产品)
    别名
    ANOP3 antibody, MCOPS3 antibody, RGD1565646 antibody, Sox-2 antibody, lcc antibody, ysb antibody, cb236 antibody, wu:fb83g04 antibody, wu:fc14d07 antibody, zgc:65860 antibody, zgc:77389 antibody, SRY-box2 antibody, Xsox-2 antibody, anop3 antibody, mcops3 antibody, sox-2 antibody, SRY-box 2 antibody, SRY box 2 antibody, SRY (sex determining region Y)-box 2 antibody, SRY-box 2 S homeolog antibody, SOX2 antibody, Sox2 antibody, sox2 antibody, sox2.S antibody
    背景
    SOX2 is a member of the SRY-related HMG-box (SOX) family of transcription factors involved in the regulation of embryonic development and in the determination of cell fate. SOX2 is required for stem-cell maintenance in the central nervous system, and also regulates gene expression in the stomach. Mutations in this gene have been associated with optic nerve hypoplasia and with syndromic microphthalmia, a severe form of structural eye malformation. The role of SOX2 in embryonic development suggested that it might be useful in the creation of stem cells that might be useful in cell replacement therapies in the treatment of degenerative diseases. Artificial stem cells, termed induced pluripotent stem (iPS) cells, can be created by expressing SOX2 and the transcription factors POU5F1, Klf4 and Lin28 along with c-Myc in mouse fibroblasts. Other experiments have shown that iPS cells could be generated using expression plasmids expressing POU5F1, SOX2, KlfF4 and c-Myc, eliminating the need for virus introduction.Synonyms: ANOP3, MCOPS3, SRY (sex determining region Y)-box 2, SRY-box 2, SRY-related HMG-box gene 2, Transcription factor SOX-2
    基因ID
    6657
    NCBI登录号
    NP_003097
    途径
    Dopaminergic Neurogenesis, Sensory Perception of Sound, Stem Cell Maintenance, Cell RedoxHomeostasis
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