SLPI 抗体 (Center)
(1 reference)Quick Overview for SLPI 抗体 (Center) (ABIN500774)
抗原
See all SLPI 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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特异性
- This antibody detects Antileukoproteinase (ALP).
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse
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纯化方法
- Peptide affinity chromatography
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免疫原
- SLPI antibody was raised against a 17 amino acid peptide from near the center of human SLPI.
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亚型
- IgG
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anti-Secretory Leukocyte Peptidase Inhibitor (SLPI) (AA 20-131) antibody
SLPI 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Secretory Leukocyte Peptidase Inhibitor (SLPI) (AA 26-132) antibodySLPI 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Secretory Leukocyte Peptidase Inhibitor (SLPI) (AA 33-132) antibodySLPI 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3C6 unconjugated
anti-Secretory Leukocyte Peptidase Inhibitor (SLPI) antibodySLPI 适用: 人 WB, ELISA, IHC, IP, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal 31 unconjugated
anti-Secretory Leukocyte Peptidase Inhibitor (SLPI) antibodySLPI 适用: 人 WB, IP, IHC (p), FACS 宿主: 小鼠 Monoclonal 31 unconjugated
anti-Secretory Leukocyte Peptidase Inhibitor (SLPI) (N-Term) antibodySLPI 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Secretory Leukocyte Peptidase Inhibitor (SLPI) (AA 11-60) antibodySLPI 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Secretory Leukocyte Peptidase Inhibitor (SLPI) (AA 1-132) antibodySLPI 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Secretory Leukocyte Peptidase Inhibitor (SLPI) (AA 26-132) antibodySLPI 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Secretory Leukocyte Peptidase Inhibitor (SLPI) (N-Term) antibodySLPI 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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: "Increased secretory leukocyte protease inhibitor (SLPI) production by highly metastatic mouse breast cancer cells." in: PLoS ONE, Vol. 9, Issue 8, pp. e104223, (2015) (PubMed).
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: "Increased secretory leukocyte protease inhibitor (SLPI) production by highly metastatic mouse breast cancer cells." in: PLoS ONE, Vol. 9, Issue 8, pp. e104223, (2015) (PubMed).
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- SLPI (Secretory Leukocyte Peptidase Inhibitor (SLPI))
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别名
- Antileukoproteinase (ALP)
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背景
- Secretory leukocyte protease inhibitor (SLPI) is produced at mucosal surfaces, primarily the upper respiratory tract and is thought to play an important role in the antiprotease defense mechanism of the lung. SLPI forms inhibitory complexes with numerous proteolytic enzymes such as neutrophil elastase, and has been shown to possess anti-inflammatory, anti-viral, and antibacterial activities. Its expression in oral epithelial cells is stimulated by HIV-1 gp120, suggesting that SLPI is a component of the oral mucosal response to HIV-1. In peripheral blood monocytes, SLPI can inhibit NF-kB activation by inhibiting IkB degradation in the cytoplasm and competing for NF-kB binding sites in the nucleus. This attenuation of the inflammatory response may also act to suppress liver metastases and other cancer cell invasions, but promote blood-borne metastasis via an invasion-independent pathway.Synonyms: BLPI, HUSI-1, Mucus proteinase inhibitor, Protease inhibitor WAP4, SLPI, Secretory leukocyte protease inhibitor, Seminal proteinase inhibitor, WAP four-disulfide core domain protein 4, WAP4, WFDC4
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基因ID
- 6590
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UniProt
- P03973
抗原
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