SLITRK2 抗体 (C-Term)
Quick Overview for SLITRK2 抗体 (C-Term) (ABIN500754)
抗原
See all SLITRK2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects SLITRK2 C-term. It is predicted to have no cross-reactivity to other Slitrk proteins.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Peptide affinity chromatography
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免疫原
- Slitrk2 antibody was raised against a 17 amino acid peptide from near the carboxy terminus of human Slitrk2.
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亚型
- IgG
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anti-SLIT and NTRK-Like Family, Member 2 (SLITRK2) (AA 79-111) antibody
SLITRK2 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SLIT and NTRK-Like Family, Member 2 (SLITRK2) (AA 301-315), (Extracellular) antibodySLITRK2 适用: 小鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-SLIT and NTRK-Like Family, Member 2 (SLITRK2) (Middle Region) antibodySLITRK2 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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- SLITRK2 (SLIT and NTRK-Like Family, Member 2 (SLITRK2))
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别名
- SLITRK2
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背景
- SLIT and NTRK-like family 2 (Slitrk2) is a member a protein family consisting of six homologous transmembrane proteins (Slitrk1-6) that share two conserved leucine-rich repeat domains in the extracellular domain and have significant homology to Slit, a secreted axonal growth-controlling protein. These proteins are also homologous to trk neurotrophin receptors in their intracellular domains. Expression of Slitrk proteins is highly restricted to neural and brain tumor tissues, but varies within the family. For example, Slitrk2 is expressed primarily in neurons in the ventricular layer of the brain. Like every other Slitrk protein except Slitrk1, overexpression of Slitrk2 inhibited neurite outgrowth in cultured neurons. Deletion analysis indicated that the functional difference between Slitrk2 and Slitrk1 is within their intracellular domains. At least two isoforms of this protein are known to exist.Synonyms: CXorf2, KIAA1854, SLIT and NTRK-like protein 2, SLITL1
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基因ID
- 84631
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UniProt
- Q9H156
抗原
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