SKI 抗体 (N-Term)
Quick Overview for SKI 抗体 (N-Term) (ABIN500734)
抗原
See all SKI 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects Ski. it will also bind to the Smad proteins specific to bone morphogenic proteins (BMPs) and block BMP signaling in mammalian cells.
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交叉反应 （详细）
- Species reactivity (tested):Human
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纯化方法
- Peptide affinity chromatography
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免疫原
- Ski antibody was raised against a 14 amino acid peptide from near the amino terminus of human Ski.
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亚型
- IgG
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anti-SKI Proto-Oncogene (SKI) (N-Term) antibody
SKI 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-SKI Proto-Oncogene (SKI) antibodySKI 适用: 人, 小鼠 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-SKI Proto-Oncogene (SKI) antibodySKI 适用: 人, 小鼠, 大鼠, 小鸡, 非洲爪蟾 WB, IHC, IP, IHC (p), ICC 宿主: 小鼠 Monoclonal G8 unconjugated
anti-SKI Proto-Oncogene (SKI) antibodySKI 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-SKI Proto-Oncogene (SKI) (AA 21-54) antibodySKI 适用: 人 WB 宿主: 兔 Polyclonal RB54389 unconjugated
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应用备注
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ELISA. Western blot: 1 - 2 μg/mL. Immunoflourescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- SKI (SKI Proto-Oncogene (SKI))
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别名
- SKI
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背景
- TGF-beta is a ubiquitously expressed cytokine that signals through the Smad protein family to regulate numerous cellular processes such as embryonic development and tumorigenesis. This signaling is negatively regulated by Ski, the mammalian homolog of the transforming protein of an avian retrovirus that induces oncogenic transformation of chicken embryo cells, and the related protein SnoN. Ski functions by binding to the Smad proteins and preventing their phosphorylation, thereby inhibiting their ability to bind DNA and activate the transcription of downstream genes.Synonyms: Proto-oncogene c-Ski, Ski oncogene, ski oncoprotein, v-ski avian sarcoma viral oncogene homolog
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基因ID
- 6497
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UniProt
- P12755
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途径
- Stem Cell Maintenance, Tube Formation, Skeletal Muscle Fiber Development
抗原
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