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SIRT2 抗体 (N-Term)

SIRT2 适用: 人, 大鼠, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN500726
发货至: 中国
  • 抗原 See all SIRT2 抗体
    SIRT2 (Sirtuin 2 (SIRT2))
    抗原表位
    • 7
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 60
    • 40
    • 36
    • 8
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 大鼠, 小鼠
    宿主
    • 58
    • 10
    • 1
    克隆类型
    • 48
    • 21
    多克隆
    标记
    • 45
    • 7
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This SIRT2 antibody is un-conjugated
    应用范围
    • 49
    • 19
    • 12
    • 12
    • 12
    • 10
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    特异性
    This antibody detects SIRT2 / SIR2 at N-term.
    交叉反应 (详细)
    Species reactivity (tested):Human, mouse, rat
    纯化方法
    Peptide affinity chromtography
    免疫原
    SIRT2 antibody was raised against a 17 amino acid peptide near the amino terminus of the human SIRT2.
    亚型
    IgG
    Top Product
    Discover our top product SIRT2 Primary Antibody
  • 应用备注
    ELISA. Western blot: 2.5 - 5 μg/mL. Immunohistochemistry on paraffin sections.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    限制
    仅限研究用
  • 缓冲液
    PBS containing 0.02 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freezing and thawing.
    储存条件
    4 °C/-20 °C
    储存方法
    Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
  • 抗原
    SIRT2 (Sirtuin 2 (SIRT2))
    别名
    SIRT2 / SIR2 (SIRT2 产品)
    别名
    CG5085 antibody, D.mel2 antibody, Dmel\\CG5085 antibody, SIRT2 antibody, dSIRT2 antibody, sir2 antibody, Sirt2 antibody, BmSirt2 antibody, AtSRT2 antibody, SIRTUIN 2 antibody, T2K12.8 antibody, sirtuin 2 antibody, SIR2 antibody, SIR2L antibody, SIR2L2 antibody, 5730427M03Rik antibody, Sir2l antibody, wu:fb57d05 antibody, zgc:55966 antibody, zgc:77003 antibody, Sirtuin 2 antibody, sirtuin 2 antibody, sirtuin 2 S homeolog antibody, NAD-dependent deacetylase sirtuin 2 homolog antibody, sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae) antibody, Sirt2 antibody, SIRT2 antibody, sirt2.S antibody, SRT2 antibody, sirt2 antibody
    背景
    Autophagy, the process of bulk degradation of cellular proteins through an autophagosomic-lysosomal pathway is important for normal growth control and may be defective in tumor cells. It is involved in the preservation of cellular nutrients under starvation conditions as well as the normal turnover of cytosolic components. This process is negatively regulated by TOR (Target of rapamycin) through phosphorylation of autophagy protein APG1. ATG16, another member of the autophagy protein family, forms a complex with the ATG5-ATG12 conjugate. This multimeric protein has been shown to be essential for autophagosome formation in both yeast and mammals and targets the ATG5-ATG12 complex to the autophagic isolation membrane during the formation of the autophagosome. Because mammalian ATG16 has seven WD-repeats in its C-terminal domain, it has been suggested that these may form a platform for further protein-protein interactions. Multiple isoforms of ATG16 are known to exist.Synonyms: NAD-dependent deacetylase sirtuin-2, SIR2-like protein 2, SIR2L, SIR2L2, SIRT-2, sirtuin (silent mating type information regulation 2 homolog) 2 (S. cerevisiae), sirtuin 2, sirtuin type 2, sirtuin-2
    基因ID
    22933
    NCBI登录号
    NP_036369
    UniProt
    Q8IXJ6
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