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SIRPA 抗体 (C-Term)

Name: SIRPA 抗体 (C-Term)
SKU: ABIN500722
Availability: OutOfStock

SIRPA 适用: 人, 小鼠, 大鼠 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated

Western blot analysis of SIRP alpha in THP-1 whole cell lysate with this product at 0. (SIRPA 抗体 (C-Term))

Immunocytochemistry of SIRP alpha in THP-1 cells with this product at 1 μg/ml. (SIRPA 抗体 (C-Term))

2 images

产品编号 ABIN500722

发货至: 中国

Datasheet as PDF

抗原 See all SIRPA 抗体

SIRPA (Signal-Regulatory Protein alpha (SIRPA))
抗原表位
16

11

5

2

2

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
适用
71

38

32

10

8

4

3

3
人, 小鼠, 大鼠
宿主
58

32

1
兔
Compatible Secondaries
克隆类型
55

36
多克隆
标记
45

11

6

3

2

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1
This SIRPA antibody is un-conjugated
应用范围
56

46

19

19

13

12

11

10

9

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)

特异性

This antibody is directed against CD172a / SIRPA C-term. 75-110 kDa bands should be detected and it recognizes SIRP alpha 1, 2 and 3.

交叉反应（详细）

Species reactivity (tested):Human, Mouse, Rat.

纯化方法

DEAE Chromatography

免疫原

SIRP alpha antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human SIRP alpha 1. .Remarks: The sequences of the immunogenic peptide differ from those of Mouse, Rat and Bovine by one amino acid.

亚型

IgG

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anti-Signal-Regulatory Protein alpha (SIRPA) (AA 31-370) antibody
SIRPA 适用: 人 FACS, ELISA, IP, IF 宿主: 兔 Monoclonal DM8 unconjugated

anti-Signal-Regulatory Protein alpha (SIRPA) (AA 395-504) antibody
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anti-Signal-Regulatory Protein alpha (SIRPA) (AA 56-296) antibody
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anti-Signal-Regulatory Protein alpha (SIRPA) (C-Term) antibody
SIRPA 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Signal-Regulatory Protein alpha (SIRPA) antibody
SIRPA 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated

anti-Signal-Regulatory Protein alpha (SIRPA) (AA 151-250) antibody
SIRPA 适用: 人, 小鼠 WB, FACS, ELISA 宿主: 兔 Polyclonal unconjugated

anti-Signal-Regulatory Protein alpha (SIRPA) (AA 105-324) antibody
SIRPA 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-Signal-Regulatory Protein alpha (SIRPA) (AA 31-373) antibody
SIRPA 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

应用备注

ELISA. Western blot (0.5-1 μg/mL). Whole cell lysate from THP-1 cells can be used as positivecontrol. Immunoflourescence.

限制

仅限研究用
浓度

1.0 mg/mL

缓冲液

PBS, 0.02 % Sodium Azide

储存液

Sodium azide

注意事项

This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freezing and thawing.

储存条件

4 °C/-20 °C

储存方法

Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
抗原

SIRPA (Signal-Regulatory Protein alpha (SIRPA))

别名

CD172a / SIRPA (SIRPA 产品)

别名

BIT antibody, CD172A antibody, MFR antibody, MYD-1 antibody, P84 antibody, PTPNS1 antibody, SHPS1 antibody, SIRP antibody, SIRPA antibody, SIRP-A1 antibody, SIRP-B1 antibody, AI835480 antibody, Bit antibody, CD172a antibody, Ptpns1 antibody, SHP-1 antibody, SHPS-1 antibody, swc3 antibody, signal regulatory protein alpha antibody, myeloperoxidase antibody, signal-regulatory protein alpha antibody, tyrosine-protein phosphatase non-receptor type substrate 1 antibody, SIRPA antibody, MPO antibody, LOC458039 antibody, LOC100400378 antibody, LOC100590224 antibody, Sirpa antibody

背景

Protein tyrosine phosphatases (PTPases) SHP-1 and SHP-2 are critical regulators in the intracellular signaling pathways that result in cell responses such as mitosis, differentiation, migration, survival, transformation or death. SHP-2 is a signal transducer for several receptor tyrosine kinases and cytokine receptors. A novel SHP-2 associated glycoprotein was recently cloned from human, rat, mouse and cattle by several labs and was designated SIRPalpha, SHPS-1, MyD-1, BIT and p84. SIRPalpha is a new gene family containing at least fifteen members. SIRPalpha is a substrate of many activated tyrosine kinases such as insulin receptor, EGFR, PDGFR and src, and a specific docking protein for SHP-2. SIRPalpha has regulatory effects on cellular responses induced by serum, growth factors, insulin, oncogenes, growth hormones and cell adhesion and plays a general role in different physiological and pathological processes.Synonyms: BIT, Brain Ig-like molecule with tyrosine-based activation motifs, CD172 antigen-like family member A, Inhibitory receptor SHPS-1, MFR, MYD1, Macrophage fusion receptor, MyD-1 antigen, PTPNS1, SHP substrate 1, SHPS-1, SHPS1, Signal-regulatory protein alpha-1, Sirp-alpha-2, Sirp-alpha-3, Tyrosine-protein phosphatase non-receptor type substrate 1, p84

分子量

75-110 kDa

基因ID

140885

NCBI登录号

NP_542970

UniProt

P78324