SIRPA 抗体 (C-Term)
Quick Overview for SIRPA 抗体 (C-Term) (ABIN500722)
抗原
See all SIRPA 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody is directed against CD172a / SIRPA C-term. 75-110 kDa bands should be detected and it recognizes SIRP alpha 1, 2 and 3.
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交叉反应 （详细）
- Species reactivity (tested):Human, Mouse, Rat.
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纯化方法
- DEAE Chromatography
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免疫原
- SIRP alpha antibody was raised against a peptide corresponding to amino acids near the carboxy terminus of human SIRP alpha 1. .Remarks: The sequences of the immunogenic peptide differ from those of Mouse, Rat and Bovine by one amino acid.
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亚型
- IgG
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anti-Signal-Regulatory Protein alpha (SIRPA) (AA 28-507) antibody
SIRPA 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 4C7 unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) (AA 235-373) antibodySIRPA 适用: 人 FACS, ELISA 宿主: 小鼠 Monoclonal 2H7E2 unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) (AA 395-504) antibodySIRPA 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) (AA 105-324) antibodySIRPA 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) (AA 56-296) antibodySIRPA 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) (C-Term) antibodySIRPA 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) antibodySIRPA 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) (AA 151-250) antibodySIRPA 适用: 人, 小鼠 WB, FACS, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) (AA 31-373) antibodySIRPA 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Signal-Regulatory Protein alpha (SIRPA) antibodySIRPA 适用: Pig WB, FACS, IP, IHC (p), IHC (fro) 宿主: 小鼠 Monoclonal BL1H7 unconjugated
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应用备注
- ELISA. Western blot (0.5-1 μg/mL). Whole cell lysate from THP-1 cells can be used as positivecontrol. Immunoflourescence.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS, 0.02 % Sodium Azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
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- SIRPA (Signal-Regulatory Protein alpha (SIRPA))
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别名
- CD172a / SIRPA
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背景
- Protein tyrosine phosphatases (PTPases) SHP-1 and SHP-2 are critical regulators in the intracellular signaling pathways that result in cell responses such as mitosis, differentiation, migration, survival, transformation or death. SHP-2 is a signal transducer for several receptor tyrosine kinases and cytokine receptors. A novel SHP-2 associated glycoprotein was recently cloned from human, rat, mouse and cattle by several labs and was designated SIRPalpha, SHPS-1, MyD-1, BIT and p84. SIRPalpha is a new gene family containing at least fifteen members. SIRPalpha is a substrate of many activated tyrosine kinases such as insulin receptor, EGFR, PDGFR and src, and a specific docking protein for SHP-2. SIRPalpha has regulatory effects on cellular responses induced by serum, growth factors, insulin, oncogenes, growth hormones and cell adhesion and plays a general role in different physiological and pathological processes.Synonyms: BIT, Brain Ig-like molecule with tyrosine-based activation motifs, CD172 antigen-like family member A, Inhibitory receptor SHPS-1, MFR, MYD1, Macrophage fusion receptor, MyD-1 antigen, PTPNS1, SHP substrate 1, SHPS-1, SHPS1, Signal-regulatory protein alpha-1, Sirp-alpha-2, Sirp-alpha-3, Tyrosine-protein phosphatase non-receptor type substrate 1, p84
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分子量
- 75-110 kDa
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基因ID
- 140885
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NCBI登录号
- NP_542970
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UniProt
- P78324
抗原
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