SIPA1L3 抗体 (N-Term)
This anti-SIPA1L3 antibody is a 兔 多克隆 antibody detecting SIPA1L3 in WB, IHC (p) 和 EIA. Suitable for 人, 小鼠 和 大鼠.
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Quick Overview for SIPA1L3 抗体 (N-Term) (ABIN500720)
抗原
SIPA1L3
(Signal-Induced Proliferation-Associated 1 Like 3 (SIPA1L3))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This SIPA1L3 antibody is un-conjugated
应用范围
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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抗原表位
- N-Term
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Peptide affinity chromatography
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免疫原
- SIPA1L3 antibody was raised against a 15 amino acid peptide from near the amino terminus of human SIPA1L3.
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亚型
- IgG
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应用备注
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ELISA. Western blot: 1 - 2 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- SIPA1L3 (Signal-Induced Proliferation-Associated 1 Like 3 (SIPA1L3))
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别名
- SIPA1L3
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背景
- Signal-induced proliferation associated-like protein 2 (SIPA1L3) is a member of the SIPA1 family of RapGAPs. SIPA1L3 was cloned as a novel molecular component of tight junctions and adherens junctions, suggesting that may function to balance Rap1 by counteracting RapGEFs. Recent studies of SIPA indicate that its deregulation can cause myeloproliferative stem cell disorders in mice (3) and increased metastases in human cancers. Other studies suggest SIPA1L1 may play important roles in embryo development and control of cell proliferation. Based on the amount of homology between SIPA family members, it is possible that SIPA1L3 plays other roles development and cell proliferation.Synonyms: KIAA0545, SPA-1-like protein 3, SPAL3, Signal-induced proliferation-associated 1-like protein 3
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基因ID
- 23094
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NCBI登录号
- NP_055888
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UniProt
- O60292
抗原
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