SIGLEC11 抗体 (C-Term)
This anti-SIGLEC11 antibody is a 兔 多克隆 antibody detecting SIGLEC11 in WB, IHC (p) 和 EIA. Suitable for 人.
Quick Overview for SIGLEC11 抗体 (C-Term) (ABIN500714)
抗原
See all SIGLEC11 抗体
SIGLEC11
(Sialic Acid Binding Ig-Like Lectin 11 (SIGLEC11))
适用
人
宿主
兔
克隆类型
多克隆
标记
This SIGLEC11 antibody is un-conjugated
应用范围
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
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抗原表位
- C-Term
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特异性
- This antibody detects Siglec11. It will not cross-react with Siglec10. Despite its predicted size, Siglec11 migrates at a higher than expected molecular weight in SDS-PAGE.
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交叉反应 （详细）
- Species reactivity (tested):Human
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纯化方法
- Peptide affinity chromatography
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免疫原
- Siglec11 antibody was raised against an 18 amino acid peptide from near the carboxy terminus of human Siglec11.
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亚型
- IgG
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anti-Sialic Acid Binding Ig-Like Lectin 11 (SIGLEC11) (AA 251-350) antibody
SIGLEC11 适用: 人 ELISA, WB, IF (cc), IF (p), IHC (p), IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- SIGLEC11 (Sialic Acid Binding Ig-Like Lectin 11 (SIGLEC11))
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别名
- SIGLEC11
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背景
- Siglecs are sialic acid-binding lectins of the immunoglobulin superfamily that are mainly expressed in cells of the hematopoietic system. Siglec11 is unlike other siglecs in that it binds specifically to a2-8-linked sialic acids and is not found in peripheral blood leukocytes but instead on macrophages of various tissues. Siglec11 is highly homologous to Siglec10 over their extracellular domain but not over their cytoplasmic domain, suggesting that Siglec11 arose through gene duplication followed by a recombination event involving another ancestral siglec gene. Following treatment of Siglec11-transfected cells with pervanadate, Siglec11 becomes tyrosine-phosphorylated and strongly associates with SHP-1 and SHP-2. At least five isoforms of Siglec11 are known to exist.Synonyms: SIGLEC-11, Sialic acid-binding Ig-like lectin 11, Sialic acid-binding lectin 11, UNQ9222/PRO28718
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基因ID
- 114132
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NCBI登录号
- NP_443116
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UniProt
- Q96RL6
抗原
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