CAB39 抗体 (AA 201-300) (AbBy Fluor® 750)
Quick Overview for CAB39 抗体 (AA 201-300) (AbBy Fluor® 750) (ABIN5006973)
抗原
See all CAB39 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 201-300
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预测反应
- Human,Mouse,Rat,Dog,Cow,Pig,Horse,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human MO25 alpha/CAB39
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亚型
- IgG
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anti-Calcium Binding Protein 39 (CAB39) antibody
CAB39 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding Protein 39 (CAB39) (AA 1-341) antibodyCAB39 适用: 人 WB, PLA 宿主: 小鼠 Polyclonal unconjugated
anti-Calcium Binding Protein 39 (CAB39) (AA 28-290) antibodyCAB39 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding Protein 39 (CAB39) antibodyCAB39 适用: 人, 小鼠 WB 宿主: 小鼠 Monoclonal 198CT13-9-1 unconjugated
anti-Calcium Binding Protein 39 (CAB39) (AA 1-341) antibodyCAB39 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding Protein 39 (CAB39) (C-Term) antibodyCAB39 适用: 人, 小鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding Protein 39 (CAB39) (C-Term) antibodyCAB39 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Bat, 小鸡, 猴, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding Protein 39 (CAB39) (C-Term) antibodyCAB39 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding Protein 39 (CAB39) (Middle Region) antibodyCAB39 适用: 人, 小鼠, 大鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Calcium Binding Protein 39 (CAB39) (Middle Region) antibodyCAB39 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼, Saccharomyces cerevisiae WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- CAB39 (Calcium Binding Protein 39 (CAB39))
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别名
- MO25 alpha/CAB39
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背景
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Synonyms: CAB39, Calcium binding protein 39, CGI 66, CGI66, MO25 alpha, MO25, Mouse protein 25 alpha, Protein Mo25.
Background: Mouse protein 25 alpha (MO25 alpha, CAB39) is a 40- kDa protein that, together with the STE20-related adaptor-alpha (STRAD alpha) pseudo kinase, forms a regulatory complex capable of stimulating the activity of the LKB1 tumor suppressor protein kinase. The latter is mutated in the inherited Peutz-Jeghers cancer syndrome (PJS). CAB39 binds directly to a conserved Trp-Glu-Phe sequence at the STRAD alpha C terminus, markedly enhancing binding of STRAD alpha to LKB1 and increasing LKB1 catalytic activity. Skeletal muscle contraction results in the phosphorylation and activation of the AMP-activated protein kinase (AMPK) by an upstream kinase (AMPKK). The LKB1-STE-related adaptor (STRAD)-mouse protein 25 (MO25) complex is the major AMPKK in skeletal muscle, however, LKB1-STRAD-MO25 activity is not increased by muscle contraction. This relationship suggests that phosphorylation of AMPK by LKB1-STRAD-MO25 during skeletal muscle contraction may be regulated by allosteric mechanisms.
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基因ID
- 51719
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途径
- AMPK Signaling
抗原
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