FBXL20 抗体 (C-Term)
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Quick Overview for FBXL20 抗体 (C-Term) (ABIN500690)
抗原
See all FBXL20 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody detects FBXL20 at C-term.
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Peptide affinity chromatography
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免疫原
- FBXL20 antibody was raised against a 18 amino acid peptide near the carboxy terminus of the human FBXL20.
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亚型
- IgG
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anti-F-Box and Leucine-Rich Repeat Protein 20 (FBXL20) (AA 1-137) antibody
FBXL20 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-F-Box and Leucine-Rich Repeat Protein 20 (FBXL20) (AA 1-436) antibodyFBXL20 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 2G1 unconjugated
anti-F-Box and Leucine-Rich Repeat Protein 20 (FBXL20) (AA 110-159) antibodyFBXL20 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-F-Box and Leucine-Rich Repeat Protein 20 (FBXL20) (AA 176-225) antibodyFBXL20 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, Bat, 猴, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-F-Box and Leucine-Rich Repeat Protein 20 (FBXL20) (N-Term) antibodyFBXL20 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA. Western blot: 0.5 - 1 μg/mL. Immunohistochemistry on paraffin sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to one month or (in aliquots) at -20 °C for longer.
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- FBXL20 (F-Box and Leucine-Rich Repeat Protein 20 (FBXL20))
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别名
- FBXL20
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背景
- Members of the F-box protein family, such as Scrapper, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1, cullin, and F-box proteins, act as protein-ubiquitin ligases. Scrapper is selectively expressed in the brain, broadly expressed within the mouse CNS and is abundant at presynaptic membrane. Scrapper has orthologs in C. elegans, D. melanogaster, and mammals which suggests that it might function as an important membrane-localized E3 ligase in various species. Scrapper is a major presynaptic E3 ubiquitin ligase that acts through RIM1a via degradation and the ubiquitin-proteasome-system (UPS) pathway to critically regulate synaptic transmission. This identifies protein degradation as a mechanism for holding synaptic communication in check.Synonyms: F-box and leucine-rich repeat protein 20, F-box/LRR-repeat protein 2-like, F-box/LRR-repeat protein 20, FBL2
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基因ID
- 84961
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NCBI登录号
- NP_116264
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UniProt
- Q96IG2
抗原
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